Bovine Proinsulin antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Bovine Proinsulin antibodies pairs and antigen for animal health (animal Bovines/Cattle type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Ruminants disease testing products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Bovine Proinsulin, an intricate 86-amino acid peptide hormone, occupies a pivotal position in the complex orchestra of insulin biosynthesis within cattle. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initiation of insulin production.

The journey of Cattle Proinsulin begins with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide, an integral component of proinsulin, is significant for its role in insulin biosynthesis.

During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it exerts its profound influence on glucose metabolism.

The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. While it does not possess the same glucose-lowering properties as insulin, research suggests that the C-peptide may have independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.

About GDU