Bovine YKL-40 antibody and antigen (recombinant protein)

Diagnostic anti-Bovine YKL-40 antibodies pairs and antigen for animal health (animal Bovines/Cattle Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-YKL-40-Ag01Bovine YKL-40$3090.00
GMP-BOV-YKL-40-Ab01Anti-Bovine YKL-40 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-YKL-40-Ab02Anti-Bovine YKL-40 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-YKL-40-Ab03Anti-Bovine YKL-40 human monoclonal antibody (mAb)$3090.00
GMP-BOV-YKL-40-Ab04Anti-Bovine YKL-40 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-YKL-40-Ag01
Product NameBovine YKL-40
Target/BiomarkerBovine YKL-40
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine YKL-40 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsBovine YKL-40
Product descriptionRecombinant Bovine YKL-40 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-YKL-40-Ab01,GMP-BOV-YKL-40-Ab02
Target/BiomarkerBovine YKL-40
Product NameAnti-Bovine YKL-40 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine YKL-40 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine YKL-40 antibodies in Bovine YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine YKL-40 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine YKL-40 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-YKL-40-Ab03,GMP-BOV-YKL-40-Ab04
Target/BiomarkerBovine YKL-40
Product NameAnti-Bovine YKL-40 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine YKL-40 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine YKL-40 antibodies in Bovine YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Product descriptionAnti-Bovine YKL-40 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine YKL-40, a glycoprotein with a molecular weight of approximately 40 kDa, emerges as a captivating player in the intricate orchestra of bovine immune responses and tissue dynamics. While it shares structural features with chitinases, it stands apart by virtue of its absence of chitinase activity. Its presence is pervasive in various bovine tissues, with prominent expression in the liver, kidneys, lungs, and immune cells.

    Structurally, Bovine YKL-40 is characterized by its unique chitin-binding domain, which hints at its involvement in tissue remodeling and repair. The glycosylation of this protein enhances its stability and modulates its functions, particularly within the context of inflammation.

    The regulation of Bovine YKL-40 expression is meticulously orchestrated, with immune cells, including macrophages and neutrophils, being prominent sources. These cells respond to inflammatory signals by producing YKL-40, marking it as a pro-inflammatory mediator and a sentinel of immune system activation.

    Beyond its role in immune responses, Bovine YKL-40 is intricately linked to tissue remodeling processes. In conditions marked by tissue injury and repair, such as wound healing and fibrosis, YKL-40's interactions with fibroblasts and epithelial cells gain prominence. It appears to modulate cellular activities associated with extracellular matrix turnover and tissue restructuring.



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