Canine A1M antibody and antigen (recombinant protein)

Diagnostic anti-Canine A1M antibodies pairs and antigen for animal health (animal Dog/Canine Proteinuria, preeclampsia,) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-A1M-Ag01Canine A1M$3090.00
GMP-CAN-A1M-Ab01Anti-Canine A1M mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-A1M-Ab02Anti-Canine A1M mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-A1M-Ab03Anti-Canine A1M human monoclonal antibody (mAb)$3090.00
GMP-CAN-A1M-Ab04Anti-Canine A1M human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-A1M-Ag01
Product NameCanine A1M
Target/BiomarkerCanine A1M
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine A1M antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of animal Dog/Canine with Proteinuria, preeclampsia,.
TagHis
Reconized/Reactive SpecicsCanine A1M
Product descriptionRecombinant Canine A1M protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-A1M-Ab01,GMP-CAN-A1M-Ab02
Target/BiomarkerCanine A1M
Product NameAnti-Canine A1M mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine A1M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine A1M antibodies in Canine A1M level test of animal Dog/Canine with Proteinuria, preeclampsia,.
Product descriptionAnti-Canine A1M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine A1M antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-A1M-Ab03,GMP-CAN-A1M-Ab04
Target/BiomarkerCanine A1M
Product NameAnti-Canine A1M human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine A1M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine A1M antibodies in Canine A1M level test of animal Dog/Canine with Proteinuria, preeclampsia,.
Product descriptionAnti-Canine A1M mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Dog/Canine Alpha-1-Microglobulin (A1M) emerges as an indispensable guardian of canine health, offering multifaceted protection against oxidative damage and tissue injury. Structurally, A1M is a glycoprotein characterized by its low molecular weight and intricate polypeptide chain, consisting of approximately 183 amino acids. Its primary site of synthesis is the liver, where it is meticulously crafted and subsequently released into the circulatory system, ready to execute its vital functions.

    At the heart of A1M's significance lies its role as a stalwart defender against oxidative stress. This biomarker stands poised to intercept and neutralize free radicals, highly reactive molecules that, when left unchecked, can inflict extensive damage to cellular structures, including proteins, lipids, and DNA. By harnessing its antioxidant prowess, A1M shields canine cells from the ravages of oxidative stress, ensuring the preservation of cellular integrity.

    Beyond its antioxidant functions, A1M exhibits a remarkable capacity to counteract tissue injury. It achieves this by forming complexes with substances generated during tissue damage, thereby preventing their toxic effects. A1M's multifunctional nature extends to its ability to bind heme, a molecule released during the breakdown of hemoglobin. By sequestering heme, A1M curtails its potential for tissue harm, offering a crucial line of defense in situations like hemolysis or hemorrhage.



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