Canine ACRV1 antibody and antigen (recombinant protein)

Diagnostic anti-Canine ACRV1 antibodies pairs and antigen for animal health (animal Dog/Canine Fertilization) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-ACRV1-Ag01Canine ACRV1$3090.00
GMP-CAN-ACRV1-Ab01Anti-Canine ACRV1 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACRV1-Ab02Anti-Canine ACRV1 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACRV1-Ab03Anti-Canine ACRV1 human monoclonal antibody (mAb)$3090.00
GMP-CAN-ACRV1-Ab04Anti-Canine ACRV1 human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-ACRV1-Ag01
Product NameCanine ACRV1
Target/BiomarkerCanine ACRV1
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine ACRV1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACRV1 level test of animal Dog/Canine with Fertilization.
TagHis
Reconized/Reactive SpecicsCanine ACRV1
Product descriptionRecombinant Canine ACRV1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACRV1-Ab01,GMP-CAN-ACRV1-Ab02
Target/BiomarkerCanine ACRV1
Product NameAnti-Canine ACRV1 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine ACRV1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACRV1 antibodies in Canine ACRV1 level test of animal Dog/Canine with Fertilization.
Product descriptionAnti-Canine ACRV1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACRV1 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACRV1-Ab03,GMP-CAN-ACRV1-Ab04
Target/BiomarkerCanine ACRV1
Product NameAnti-Canine ACRV1 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine ACRV1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACRV1 antibodies in Canine ACRV1 level test of animal Dog/Canine with Fertilization.
Product descriptionAnti-Canine ACRV1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine ACRV1, or Acrosome Protein ACRV1, represents a linchpin in the intricate machinery of canine reproduction. This protein, primarily housed within the acrosome, a specialized organelle that crowns the head of mature sperm, holds the key to one of life's most critical processes—fertilization.

    Structurally, ACRV1 is a glycoprotein integral to the acrosome's composition. The acrosome is a sac-like structure containing enzymes and proteins crucial for sperm-egg interaction and penetration. ACRV1's role begins at the moment of sperm-egg contact, where it participates in sperm-egg binding and membrane fusion. These initial steps set the stage for the subsequent acrosomal reaction.

    The acrosomal reaction, orchestrated in part by ACRV1, is a cascade of events that unfolds as the sperm approaches the egg. It entails the release of acrosomal enzymes that digest the zona pellucida, a glycoprotein-rich layer surrounding the egg. ACRV1 contributes to the breakdown of the zona pellucida, facilitating the penetration of the egg's protective layers.

    Furthermore, ACRV1's function is not limited to the moment of fertilization. It is believed to play a role in the formation and maintenance of the acrosome itself. A well-formed and intact acrosome is vital for sperm function, and disruptions in ACRV1 expression or function can affect the acrosome's structural integrity.



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