Canine ACTH antibody and antigen (recombinant protein)

Diagnostic anti-Canine ACTH antibodies pairs and antigen for animal health (animal Dog/Canine pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-ACTH-Ag01Canine ACTH$3090.00
GMP-CAN-ACTH-Ab01Anti-Canine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACTH-Ab02Anti-Canine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACTH-Ab03Anti-Canine ACTH human monoclonal antibody (mAb)$3090.00
GMP-CAN-ACTH-Ab04Anti-Canine ACTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-ACTH-Ag01
Product NameCanine ACTH
Target/BiomarkerCanine ACTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine ACTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACTH level test of animal Dog/Canine with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
TagHis
Reconized/Reactive SpecicsCanine ACTH
Product descriptionRecombinant Canine ACTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACTH-Ab01,GMP-CAN-ACTH-Ab02
Target/BiomarkerCanine ACTH
Product NameAnti-Canine ACTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACTH antibodies in Canine ACTH level test of animal Dog/Canine with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Canine ACTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACTH-Ab03,GMP-CAN-ACTH-Ab04
Target/BiomarkerCanine ACTH
Product NameAnti-Canine ACTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACTH antibodies in Canine ACTH level test of animal Dog/Canine with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Canine ACTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Adrenocorticotropic Hormone (ACTH) is a pivotal player in the endocrine system of dogs, orchestrating the body's response to stressors and maintaining hormonal balance. Structurally, ACTH is a 39-amino acid peptide hormone produced and secreted by the anterior pituitary gland. It belongs to the family of melanocortins, a group of hormones with diverse physiological functions.

    The primary role of ACTH lies in its regulation of the adrenal glands, specifically the adrenal cortex. In response to stress or changes in the internal environment, the hypothalamus releases corticotropin-releasing hormone (CRH). CRH, in turn, triggers the secretion of ACTH from the anterior pituitary gland. ACTH then enters the bloodstream and travels to the adrenal cortex.

    In the adrenal cortex, ACTH binds to specific receptors on the surface of adrenal cells, setting in motion a series of intracellular events. These events lead to the synthesis and release of cortisol, a corticosteroid hormone with far-reaching effects on the body.

    Cortisol, often referred to as the "stress hormone," plays a pivotal role in metabolic regulation, immune function, and the body's response to various stressors. It helps the body adapt to stressful situations by increasing blood glucose levels, suppressing the immune system, and modulating inflammation. Cortisol also influences other physiological processes, including protein and fat metabolism, electrolyte balance, and cardiovascular function.



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