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Canine AD7c-NTP antibody and antigen (recombinant protein)
Diagnostic anti-Canine AD7c-NTP antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-AD7c-NTP-Ag01 | Canine AD7c-NTP | $3090.00 |
| GMP-CAN-AD7c-NTP-Ab01 | Anti-Canine AD7c-NTP mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-AD7c-NTP-Ab02 | Anti-Canine AD7c-NTP mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-AD7c-NTP-Ab03 | Anti-Canine AD7c-NTP human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-AD7c-NTP-Ab04 | Anti-Canine AD7c-NTP human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-AD7c-NTP-Ag01 |
| Product Name | Canine AD7c-NTP |
| Target/Biomarker | Canine AD7c-NTP |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine AD7c-NTP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AD7c-NTP level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Tag | His | Reconized/Reactive Specics | Canine AD7c-NTP |
| Product description | Recombinant Canine AD7c-NTP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-AD7c-NTP-Ab01,GMP-CAN-AD7c-NTP-Ab02 |
| Target/Biomarker | Canine AD7c-NTP |
| Product Name | Anti-Canine AD7c-NTP mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine AD7c-NTP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine AD7c-NTP antibodies in Canine AD7c-NTP level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Product description | Anti-Canine AD7c-NTP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine AD7c-NTP antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-AD7c-NTP-Ab03,GMP-CAN-AD7c-NTP-Ab04 |
| Target/Biomarker | Canine AD7c-NTP |
| Product Name | Anti-Canine AD7c-NTP human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine AD7c-NTP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine AD7c-NTP antibodies in Canine AD7c-NTP level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Product description | Anti-Canine AD7c-NTP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Canine AD-associated Neuronal Thread Protein (AD7c-NTP) represents a pivotal protagonist in the intricate narrative of canine neurodegeneration. Structurally reminiscent of its human counterpart, AD7c-NTP is a neuronal protein that finds itself intimately woven into the fabric of neurofibrillary tangle formation, a central pathological feature shared with Alzheimer's disease (AD).
The journey of AD7c-NTP begins within the canine brain, where it partakes in the complex choreography of neurofibrillary tangle assembly. These tangles, characterized by their twisted filaments primarily composed of AD7c-NTP, are emblematic of cognitive dysfunction and memory impairment in dogs. This phenomenon parallels the neurofibrillary tangles seen in humans with AD, underscoring the evolutionary conservation of neurodegenerative processes.
At a molecular level, the aggregation of AD7c-NTP and its entanglement with other associated proteins give rise to the neurofibrillary tangles that disrupt the normal architecture and function of neurons. This disruption leads to neuronal death and synapse loss, ultimately manifesting as the cognitive deficits observed in dogs afflicted with canine cognitive dysfunction syndrome (CCDS).
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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