Canine B2M antibody and antigen (recombinant protein)

Diagnostic anti-Canine B2M antibodies pairs and antigen for animal health (animal Dog/Canine renal disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-B2M-Ag01Canine B2M$3090.00
GMP-CAN-B2M-Ab01Anti-Canine B2M mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-B2M-Ab02Anti-Canine B2M mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-B2M-Ab03Anti-Canine B2M human monoclonal antibody (mAb)$3090.00
GMP-CAN-B2M-Ab04Anti-Canine B2M human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-B2M-Ag01
Product NameCanine B2M
Target/BiomarkerCanine B2M
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine B2M antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of animal Dog/Canine with renal disease.
TagHis
Reconized/Reactive SpecicsCanine B2M
Product descriptionRecombinant Canine B2M protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-B2M-Ab01,GMP-CAN-B2M-Ab02
Target/BiomarkerCanine B2M
Product NameAnti-Canine B2M mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine B2M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine B2M antibodies in Canine B2M level test of animal Dog/Canine with renal disease.
Product descriptionAnti-Canine B2M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine B2M antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-B2M-Ab03,GMP-CAN-B2M-Ab04
Target/BiomarkerCanine B2M
Product NameAnti-Canine B2M human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine B2M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine B2M antibodies in Canine B2M level test of animal Dog/Canine with renal disease.
Product descriptionAnti-Canine B2M mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine B2M, or Beta-2 Microglobulin, stands as a remarkable protein, a molecular sentinel that orchestrates the intricate symphony of the canine immune system. This small globular protein plays a pivotal role in canine health, serving as an essential component of major histocompatibility complex (MHC) class I molecules.

    The MHC class I molecules, in partnership with Canine B2M, form a crucial part of immune surveillance in dogs. These molecules are like molecular flags displayed on the surface of nearly every nucleated cell in a dog's body. Their primary function is to present fragments of intracellular pathogens or abnormal cellular proteins to cytotoxic T cells, the immune system's elite enforcers. This presentation is akin to a molecular "Wanted" poster, enabling the immune system to identify and eliminate infected or aberrant cells with precision.

    Canine B2M plays a vital role in ensuring the proper functioning of MHC class I molecules. Without B2M, these molecules would not be efficiently transported to the cell surface or would be susceptible to premature degradation. This would compromise the dog's immune surveillance, akin to dimming the lights on a security camera. Canine B2M steps in as the molecular caretaker, maintaining the vigilance of the immune system and ensuring that threats are promptly detected and dealt with.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.