Canine CA15-3 antibody and antigen (recombinant protein)

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Diagnostic anti-Canine CA15-3 antibodies pairs and antigen for animal health (animal Dog/Canine breast cancer ) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

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Target/Biomarker Information

Cancer Antigen 15-3 (CA15-3) is a biomarker of growing importance in the context of canine biology. Originally identified and characterized in humans, CA15-3 has since been found to have homologous counterparts in various species, including dogs. This glycoprotein plays a pivotal role in the physiology of canines, with its primary association lying in the realm of mammary tissue development and health.

In female dogs, CA15-3 emerges as a key player within the intricate landscape of mammary gland physiology. The mammary glands are a crucial anatomical feature in female dogs, serving the vital function of providing nutrition to offspring during lactation. Consequently, any disturbances in mammary gland health can have far-reaching consequences for the well-being of the individual dog, particularly intact females.

CA15-3 is a biomarker that exhibits dynamic expression patterns within the canine mammary glands. Its levels can vary according to physiological factors, and notable changes are observed during different stages of the reproductive cycle and lactation. This dynamic modulation is not merely incidental; it is deeply intertwined with the regulation of mammary tissue development and function. Hence, CA15-3's role as an indicator of mammary gland health extends beyond simple biomarker status—it is a critical sentinel, offering insights into the dynamic changes occurring within this tissue.

Furthermore, CA15-3 in dogs is of particular interest due to its association with mammary tumors, which are relatively common in female dogs. Mammary tumors in dogs can range from benign to malignant, with varying degrees of impact on the dog's health and prognosis. CA15-3 levels have shown promise as diagnostic tools, as elevated levels often correlate with the presence of mammary tumors and their potential malignancy. This has significant implications for veterinarians and dog owners alike, as the early detection of mammary tumors can lead to timely intervention and improved treatment outcomes.

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