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Canine CYFRA21-1 antibody and antigen (recombinant protein)
Diagnostic anti-Canine CYFRA21-1 antibodies pairs and antigen for animal health (animal Dog/Canine bronchopulmonary dysplasia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-CYFRA21-1-Ag01 | Canine CYFRA21-1 | $3090.00 |
| GMP-CAN-CYFRA21-1-Ab01 | Anti-Canine CYFRA21-1 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-CYFRA21-1-Ab02 | Anti-Canine CYFRA21-1 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-CYFRA21-1-Ab03 | Anti-Canine CYFRA21-1 human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-CYFRA21-1-Ab04 | Anti-Canine CYFRA21-1 human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-CYFRA21-1-Ag01 |
| Product Name | Canine CYFRA21-1 |
| Target/Biomarker | Canine CYFRA21-1 |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine CYFRA21-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CYFRA21-1 level test of animal Dog/Canine with bronchopulmonary dysplasia. |
| Tag | His | Reconized/Reactive Specics | Canine CYFRA21-1 |
| Product description | Recombinant Canine CYFRA21-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-CYFRA21-1-Ab01,GMP-CAN-CYFRA21-1-Ab02 |
| Target/Biomarker | Canine CYFRA21-1 |
| Product Name | Anti-Canine CYFRA21-1 mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine CYFRA21-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine CYFRA21-1 antibodies in Canine CYFRA21-1 level test of animal Dog/Canine with bronchopulmonary dysplasia. |
| Product description | Anti-Canine CYFRA21-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine CYFRA21-1 antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-CYFRA21-1-Ab03,GMP-CAN-CYFRA21-1-Ab04 |
| Target/Biomarker | Canine CYFRA21-1 |
| Product Name | Anti-Canine CYFRA21-1 human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine CYFRA21-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine CYFRA21-1 antibodies in Canine CYFRA21-1 level test of animal Dog/Canine with bronchopulmonary dysplasia. |
| Product description | Anti-Canine CYFRA21-1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
CYFRA21-1, also known as Cytokeratin 19 Fragment 21-1, is a noteworthy biomarker within the context of dogs (canines). It originates from cytokeratin 19, a protein that plays a pivotal role in maintaining the structural integrity of epithelial cells. Epithelial cells are widespread in various tissues throughout the canine body, including the lungs and skin. When these cells undergo changes due to injury, malignancy, or other pathological processes, CYFRA21-1 fragments can be released into the bloodstream, making it a valuable indicator of epithelial cell health.
At the molecular level, CYFRA21-1 consists of specific fragments of cytokeratin 19, notably the 21-1 fragment. These soluble protein fragments can be detected through blood tests. In healthy dogs, CYFRA21-1 levels are typically low. However, when there is damage or malignancy in epithelial tissues, such as the lungs, the levels of CYFRA21-1 can significantly increase. This phenomenon makes CYFRA21-1 a crucial biomarker for assessing the health of the respiratory and epithelial systems in canines.
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