Canine FIB antibody and antigen (recombinant protein)

Diagnostic anti-Canine FIB antibodies pairs and antigen for animal health (animal Dog/Canine congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-FIB-Ag01Canine FIB$3090.00
GMP-CAN-FIB-Ab01Anti-Canine FIB mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-FIB-Ab02Anti-Canine FIB mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-FIB-Ab03Anti-Canine FIB human monoclonal antibody (mAb)$3090.00
GMP-CAN-FIB-Ab04Anti-Canine FIB human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-FIB-Ag01
Product NameCanine FIB
Target/BiomarkerCanine FIB
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine FIB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
TagHis
Reconized/Reactive SpecicsCanine FIB
Product descriptionRecombinant Canine FIB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-FIB-Ab01,GMP-CAN-FIB-Ab02
Target/BiomarkerCanine FIB
Product NameAnti-Canine FIB mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies in Canine FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Canine FIB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-FIB-Ab03,GMP-CAN-FIB-Ab04
Target/BiomarkerCanine FIB
Product NameAnti-Canine FIB human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies in Canine FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia.
Product descriptionAnti-Canine FIB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Fibrinogen, an intricate player in the dog's hemostatic orchestra, merits a closer examination. Structurally, it is a glycoprotein of considerable complexity, comprising three polypeptide chains: alpha, beta, and gamma. These chains intertwine to form a large, hexameric molecule with a molecular mass of approximately 340 kDa. Synthesized predominantly in the liver, canine fibrinogen is released into the bloodstream, where it awaits its crucial role in maintaining hemostasis.

    The cornerstone of canine fibrinogen's function lies in its conversion to fibrin, the scaffolding upon which blood clots are constructed. This conversion is orchestrated by the enzyme thrombin, which cleaves fibrinogen's alpha and beta chains, unleashing fibrin's polymerization potential. Fibrin threads emerge from this process, interweaving into a meshwork that entraps blood cells, forming the foundation of a blood clot.

    Canine fibrinogen's dynamic nature renders it a versatile biomarker. Its concentrations can fluctuate in response to various physiological and pathological stimuli. In instances of inflammation, infection, or tissue injury, fibrinogen synthesis in the liver escalates as part of the acute-phase response. This elevation serves a protective purpose, fortifying the body's ability to staunch bleeding at the site of injury.



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