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Canine FIB antibody and antigen (recombinant protein)
Diagnostic anti-Canine FIB antibodies pairs and antigen for animal health (animal Dog/Canine congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-FIB-Ag01 | Canine FIB | $3090.00 |
| GMP-CAN-FIB-Ab01 | Anti-Canine FIB mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-FIB-Ab02 | Anti-Canine FIB mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-FIB-Ab03 | Anti-Canine FIB human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-FIB-Ab04 | Anti-Canine FIB human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-FIB-Ag01 |
| Product Name | Canine FIB |
| Target/Biomarker | Canine FIB |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine FIB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia. |
| Tag | His | Reconized/Reactive Specics | Canine FIB |
| Product description | Recombinant Canine FIB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-FIB-Ab01,GMP-CAN-FIB-Ab02 |
| Target/Biomarker | Canine FIB |
| Product Name | Anti-Canine FIB mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies in Canine FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia. |
| Product description | Anti-Canine FIB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-FIB-Ab03,GMP-CAN-FIB-Ab04 |
| Target/Biomarker | Canine FIB |
| Product Name | Anti-Canine FIB human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine FIB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FIB antibodies in Canine FIB level test of animal Dog/Canine with congenital afibrinogenemia, congenital hypofibrinogenemia, fibrinogen storage disease, congenital dysfibrinogenemia, hereditary fibrinogen Aα-Chain amyloidosis, acquired dysfibrinogenemia, congenital hypodysfibrinogenemia, and cryofibrinogenemia. |
| Product description | Anti-Canine FIB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Canine Fibrinogen, an intricate player in the dog's hemostatic orchestra, merits a closer examination. Structurally, it is a glycoprotein of considerable complexity, comprising three polypeptide chains: alpha, beta, and gamma. These chains intertwine to form a large, hexameric molecule with a molecular mass of approximately 340 kDa. Synthesized predominantly in the liver, canine fibrinogen is released into the bloodstream, where it awaits its crucial role in maintaining hemostasis.
The cornerstone of canine fibrinogen's function lies in its conversion to fibrin, the scaffolding upon which blood clots are constructed. This conversion is orchestrated by the enzyme thrombin, which cleaves fibrinogen's alpha and beta chains, unleashing fibrin's polymerization potential. Fibrin threads emerge from this process, interweaving into a meshwork that entraps blood cells, forming the foundation of a blood clot.
Canine fibrinogen's dynamic nature renders it a versatile biomarker. Its concentrations can fluctuate in response to various physiological and pathological stimuli. In instances of inflammation, infection, or tissue injury, fibrinogen synthesis in the liver escalates as part of the acute-phase response. This elevation serves a protective purpose, fortifying the body's ability to staunch bleeding at the site of injury.
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GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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