Canine FSH antibody and antigen (recombinant protein)

Diagnostic anti-Canine FSH antibodies pairs and antigen for animal health (animal Dog/Canine hypergonadotrophic-hypogonadism and infertility) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-FSH-Ag01Canine FSH$3090.00
GMP-CAN-FSH-Ab01Anti-Canine FSH mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-FSH-Ab02Anti-Canine FSH mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-FSH-Ab03Anti-Canine FSH human monoclonal antibody (mAb)$3090.00
GMP-CAN-FSH-Ab04Anti-Canine FSH human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-FSH-Ag01
Product NameCanine FSH
Target/BiomarkerCanine FSH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine FSH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
TagHis
Reconized/Reactive SpecicsCanine FSH
Product descriptionRecombinant Canine FSH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-FSH-Ab01,GMP-CAN-FSH-Ab02
Target/BiomarkerCanine FSH
Product NameAnti-Canine FSH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine FSH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FSH antibodies in Canine FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
Product descriptionAnti-Canine FSH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FSH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-FSH-Ab03,GMP-CAN-FSH-Ab04
Target/BiomarkerCanine FSH
Product NameAnti-Canine FSH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine FSH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine FSH antibodies in Canine FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
Product descriptionAnti-Canine FSH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Follicle-Stimulating Hormone (FSH) in dogs, or canines, is a master regulator of reproductive processes, standing as a testament to the intricate choreography of hormonal signals that govern the fertility of these beloved animals. Structurally, FSH is a glycoprotein hormone, part of the gonadotropin family, and is synthesized and secreted by the anterior pituitary gland.

    In the female canine reproductive system, FSH plays a pivotal role in orchestrating the estrous cycle. It's the hormone responsible for nurturing the development of ovarian follicles, each housing an immature egg (oocyte). As FSH levels rise, it signals the ovaries to initiate the recruitment and growth of these follicles, a process known as folliculogenesis. FSH's influence extends further, as it primes these follicles for ovulation, a momentous event in the reproductive calendar of a female dog.

    The regulation of FSH secretion is a finely tuned process, subject to intricate feedback mechanisms. The secretion of sex hormones, such as estrogen and inhibin, exerts a dynamic influence on FSH release. This feedback system ensures the precise timing and intensity of FSH secretion, ensuring that follicular development and ovulation occur at the optimal moments within the estrous cycle.

    In the male canine reproductive system, FSH's role is no less significant. Spermatogenesis, the intricate process of sperm cell development, hinges on the stimulation provided by FSH. Within the testes, FSH acts on specialized cells called Sertoli cells. These cells provide the essential nurturing environment for developing sperm cells. Under FSH's influence, Sertoli cells create the ideal conditions for sperm maturation, fostering the production of functional and motile sperm.

    The dynamic interplay between FSH and other hormones, such as luteinizing hormone (LH), is critical for the synchronization of male and female reproductive processes. In essence, FSH represents the molecular conductor of the symphony of events that culminate in successful canine reproduction.



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