Canine H-FABP antibody and antigen (recombinant protein)

Diagnostic anti-Canine H-FABP antibodies pairs and antigen for animal health (animal Dog/Canine myocardial injury) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-H-FABP-Ag01Canine H-FABP$3090.00
GMP-CAN-H-FABP-Ab01Anti-Canine H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-H-FABP-Ab02Anti-Canine H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-H-FABP-Ab03Anti-Canine H-FABP human monoclonal antibody (mAb)$3090.00
GMP-CAN-H-FABP-Ab04Anti-Canine H-FABP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-H-FABP-Ag01
Product NameCanine H-FABP
Target/BiomarkerCanine H-FABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine H-FABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in H-FABP level test of animal Dog/Canine with myocardial injury.
TagHis
Reconized/Reactive SpecicsCanine H-FABP
Product descriptionRecombinant Canine H-FABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-H-FABP-Ab01,GMP-CAN-H-FABP-Ab02
Target/BiomarkerCanine H-FABP
Product NameAnti-Canine H-FABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine H-FABP antibodies in Canine H-FABP level test of animal Dog/Canine with myocardial injury.
Product descriptionAnti-Canine H-FABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine H-FABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-H-FABP-Ab03,GMP-CAN-H-FABP-Ab04
Target/BiomarkerCanine H-FABP
Product NameAnti-Canine H-FABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine H-FABP antibodies in Canine H-FABP level test of animal Dog/Canine with myocardial injury.
Product descriptionAnti-Canine H-FABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    H-FABP, short for Heart-Fatty Acid Binding Protein, stands as a remarkable biomarker within the realm of canine biology. This small yet pivotal protein is predominantly expressed in the heart muscle of dogs (canines) and is intricately involved in the orchestration of fatty acid metabolism within cardiomyocytes. Structurally, H-FABP is a cytoplasmic protein with a distinct binding pocket that allows it to shuttle fatty acids, an essential energy source, within cardiac muscle cells.

    The exclusive localization of H-FABP within the heart tissue underscores its importance in assessing cardiac health. Under normal physiological conditions, H-FABP levels in the bloodstream of dogs remain relatively low. However, its concentration can dramatically increase in response to cardiac stress or injury, making it an invaluable diagnostic tool for veterinarians and a source of valuable insights for pet owners.

    H-FABP's function in the heart is multifaceted. It participates in the uptake, transport, and utilization of fatty acids as an energy substrate during various physiological conditions, such as exercise or stress. However, its significance extends far beyond metabolic regulation. H-FABP's role as a biomarker becomes particularly evident when the heart encounters challenges.

    In situations where cardiac ischemia or infarction occurs, such as during a heart attack, the heart muscle undergoes a process of injury due to inadequate blood supply. This ischemic injury triggers the release of H-FABP into the bloodstream. Thus, elevated levels of H-FABP in a dog's blood can serve as an early indicator of myocardial damage, even before clinical symptoms manifest.



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