Canine IL-6 antibody and antigen (recombinant protein)

Diagnostic anti-Canine IL-6 antibodies pairs and antigen for animal health (animal Dog/Canine systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease.) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-IL-6-Ag01Canine IL-6$3090.00
GMP-CAN-IL-6-Ab01Anti-Canine IL-6 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-IL-6-Ab02Anti-Canine IL-6 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-IL-6-Ab03Anti-Canine IL-6 human monoclonal antibody (mAb)$3090.00
GMP-CAN-IL-6-Ab04Anti-Canine IL-6 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-IL-6-Ag01
Product NameCanine IL-6
Target/BiomarkerCanine IL-6
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine IL-6 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IL-6 level test of animal Dog/Canine with systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease..
TagHis
Reconized/Reactive SpecicsCanine IL-6
Product descriptionRecombinant Canine IL-6 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-IL-6-Ab01,GMP-CAN-IL-6-Ab02
Target/BiomarkerCanine IL-6
Product NameAnti-Canine IL-6 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine IL-6 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine IL-6 antibodies in Canine IL-6 level test of animal Dog/Canine with systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease..
Product descriptionAnti-Canine IL-6 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine IL-6 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-IL-6-Ab03,GMP-CAN-IL-6-Ab04
Target/BiomarkerCanine IL-6
Product NameAnti-Canine IL-6 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine IL-6 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine IL-6 antibodies in Canine IL-6 level test of animal Dog/Canine with systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease..
Product descriptionAnti-Canine IL-6 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Interleukin-6 (IL-6) stands as a multifaceted cytokine in the realm of canine health, playing a pivotal role in immune regulation and inflammation management. This biomarker is produced by a diverse array of cells, including white blood cells (leukocytes), macrophages, and fibroblasts, in response to various physiological stimuli.

    In dogs, IL-6's functions are diverse and context-dependent. It serves as both a pro-inflammatory and anti-inflammatory cytokine, responding dynamically to the body's needs. During acute infections or tissue injuries, IL-6 is released to trigger an immediate immune response, recruiting immune cells to the site of infection or injury and enhancing their activity. Moreover, IL-6 supports the liver in producing acute-phase proteins, which are essential for the body's defense mechanisms.

    However, it's essential to note that prolonged or excessive IL-6 production can lead to chronic inflammation, which is implicated in various diseases, including autoimmune disorders and certain cancers. Dysregulation of IL-6 is associated with health issues, making its measurement in dogs a valuable diagnostic tool.

    IL-6 levels can be assessed through blood tests, allowing veterinarians to gauge a dog's immune status and inflammatory state. Elevated levels of IL-6 often indicate the presence of inflammation or infection. This makes IL-6 a sensitive biomarker for diagnosing and monitoring a spectrum of canine diseases, from simple infections to complex autoimmune conditions.



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