Canine PG I antibody and antigen (recombinant protein)

Diagnostic anti-Canine PG I antibodies pairs and antigen for animal health (animal Dog/Canine atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-PG-I-Ag01Canine PG I$3090.00
GMP-CAN-PG-I-Ab01Anti-Canine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PG-I-Ab02Anti-Canine PG I mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-PG-I-Ab03Anti-Canine PG I human monoclonal antibody (mAb)$3090.00
GMP-CAN-PG-I-Ab04Anti-Canine PG I human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-PG-I-Ag01
Product NameCanine PG I
Target/BiomarkerCanine PG I
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine PG I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Dog/Canine with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
TagHis
Reconized/Reactive SpecicsCanine PG I
Product descriptionRecombinant Canine PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PG-I-Ab01,GMP-CAN-PG-I-Ab02
Target/BiomarkerCanine PG I
Product NameAnti-Canine PG I mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG I antibodies in Canine PG I level test of animal Dog/Canine with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Canine PG I mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG I antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-PG-I-Ab03,GMP-CAN-PG-I-Ab04
Target/BiomarkerCanine PG I
Product NameAnti-Canine PG I human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine PG I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG I antibodies in Canine PG I level test of animal Dog/Canine with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Product descriptionAnti-Canine PG I mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Dog/Canine Prostaglandin I (PG I), or prostacyclin, emerges as a fundamental player in the intricate orchestra of canine cardiovascular physiology. This lipid compound, belonging to the prostaglandin family, boasts hormone-like functions and carries out its pivotal duties primarily within the endothelial cells that line the inner walls of blood vessels.

    Structurally, PG I showcases a 20-carbon chain with a cyclopentane ring structure, featuring a hydroxyl group. It is synthesized through the enzymatic action of prostacyclin synthase, an enzyme found predominantly within endothelial cells. This synthesis is a tightly regulated process, ensuring that PG I is available when needed to exert its critical functions.

    PG I's primary mission in canine physiology is to maintain vascular homeostasis. It achieves this by acting as a potent vasodilator, particularly in arterioles and capillaries. When released, PG I serves as a chemical messenger that signals the adjacent smooth muscle cells in the blood vessel walls to relax. This relaxation results in vasodilation, a widening of the blood vessel lumen. The consequence is a reduction in vascular resistance and an increase in blood vessel diameter, both of which facilitate optimal blood flow throughout the canine circulatory system. By promoting proper blood pressure and ensuring adequate perfusion of tissues, PG I plays a pivotal role in safeguarding cardiovascular health in dogs.



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