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Canine PG II antibody and antigen (recombinant protein)
Diagnostic anti-Canine PG II antibodies pairs and antigen for animal health (animal Dog/Canine pernicious anemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-PG-II-Ag01 | Canine PG II | $3090.00 |
| GMP-CAN-PG-II-Ab01 | Anti-Canine PG II mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-PG-II-Ab02 | Anti-Canine PG II mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-PG-II-Ab03 | Anti-Canine PG II human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-PG-II-Ab04 | Anti-Canine PG II human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-PG-II-Ag01 |
| Product Name | Canine PG II |
| Target/Biomarker | Canine PG II |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine PG II antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of animal Dog/Canine with pernicious anemia. |
| Tag | His | Reconized/Reactive Specics | Canine PG II |
| Product description | Recombinant Canine PG II protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-PG-II-Ab01,GMP-CAN-PG-II-Ab02 |
| Target/Biomarker | Canine PG II |
| Product Name | Anti-Canine PG II mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine PG II antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG II antibodies in Canine PG II level test of animal Dog/Canine with pernicious anemia. |
| Product description | Anti-Canine PG II mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG II antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-PG-II-Ab03,GMP-CAN-PG-II-Ab04 |
| Target/Biomarker | Canine PG II |
| Product Name | Anti-Canine PG II human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine PG II antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine PG II antibodies in Canine PG II level test of animal Dog/Canine with pernicious anemia. |
| Product description | Anti-Canine PG II mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Dog/Canine Pepsinogen II (PG II) emerges as a captivating biomarker, offering profound insights into the intricacies of canine digestion. Structurally, PG II is an inactive zymogen, a precursor to the active enzyme pepsin, and it takes center stage within the gastric mucosa of the dog's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands.
The journey of PG II begins with the ingestion of food. As dietary proteins enter the canine stomach, PG II stands poised for its transformation into active pepsin. This metamorphosis unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG II to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall canine health.
Beyond its role as a digestive precursor, PG II serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG II is predominantly localized, is crucial for proper PG II secretion. Disruptions in this mucosal lining, such as those seen in gastritis, gastric ulcers, or inflammatory bowel disease, can alter PG II levels, offering valuable diagnostic insights.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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