Canine S100B antibody and antigen (recombinant protein)

Diagnostic anti-Canine S100B antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-S100B-Ag01Canine S100B$3090.00
GMP-CAN-S100B-Ab01Anti-Canine S100B mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-S100B-Ab02Anti-Canine S100B mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-S100B-Ab03Anti-Canine S100B human monoclonal antibody (mAb)$3090.00
GMP-CAN-S100B-Ab04Anti-Canine S100B human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-S100B-Ag01
Product NameCanine S100B
Target/BiomarkerCanine S100B
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine S100B antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100B level test of animal Dog/Canine with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
TagHis
Reconized/Reactive SpecicsCanine S100B
Product descriptionRecombinant Canine S100B protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-S100B-Ab01,GMP-CAN-S100B-Ab02
Target/BiomarkerCanine S100B
Product NameAnti-Canine S100B mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine S100B antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100B antibodies in Canine S100B level test of animal Dog/Canine with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
Product descriptionAnti-Canine S100B mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100B antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-S100B-Ab03,GMP-CAN-S100B-Ab04
Target/BiomarkerCanine S100B
Product NameAnti-Canine S100B human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine S100B antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100B antibodies in Canine S100B level test of animal Dog/Canine with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
Product descriptionAnti-Canine S100B mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    S100B, or S100 calcium-binding protein B, is a biomarker of significant importance within the context of dogs (canines). It belongs to the S100 protein family, a diverse group of calcium-binding proteins known for their involvement in a wide range of cellular processes. In dogs, S100B is primarily expressed in astrocytes, specialized glial cells that play a crucial role in maintaining the health and function of the central nervous system.

    S100B is distinguished by its ability to serve as a marker of neurological stress and injury. When the canine brain experiences trauma, ischemia (reduced blood supply), or neuroinflammation, S100B can be released into the bloodstream. This release can be detected through blood tests, making S100B a valuable tool for assessing the state of the central nervous system in dogs.

    The functions of S100B in canines are multifaceted. One of its prominent roles is related to neuroprotection. S100B has been shown to exert neuroprotective effects by promoting the survival and function of neurons under adverse conditions. It achieves this by regulating calcium homeostasis, influencing neuronal plasticity, and interacting with various cellular signaling pathways. These neuroprotective properties make S100B a crucial player in the brain's response to injury and stress.



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