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Canine TIMP-1 antibody and antigen (recombinant protein)
Diagnostic anti-Canine TIMP-1 antibodies pairs and antigen for animal health (animal Dog/Canine coronary artery stenosis, coronary artery lesions) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-TIMP-1-Ag01 | Canine TIMP-1 | $3090.00 |
| GMP-CAN-TIMP-1-Ab01 | Anti-Canine TIMP-1 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-TIMP-1-Ab02 | Anti-Canine TIMP-1 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-TIMP-1-Ab03 | Anti-Canine TIMP-1 human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-TIMP-1-Ab04 | Anti-Canine TIMP-1 human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-TIMP-1-Ag01 |
| Product Name | Canine TIMP-1 |
| Target/Biomarker | Canine TIMP-1 |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine TIMP-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TIMP-1 level test of animal Dog/Canine with coronary artery stenosis, coronary artery lesions. |
| Tag | His | Reconized/Reactive Specics | Canine TIMP-1 |
| Product description | Recombinant Canine TIMP-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-TIMP-1-Ab01,GMP-CAN-TIMP-1-Ab02 |
| Target/Biomarker | Canine TIMP-1 |
| Product Name | Anti-Canine TIMP-1 mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine TIMP-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TIMP-1 antibodies in Canine TIMP-1 level test of animal Dog/Canine with coronary artery stenosis, coronary artery lesions. |
| Product description | Anti-Canine TIMP-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TIMP-1 antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-TIMP-1-Ab03,GMP-CAN-TIMP-1-Ab04 |
| Target/Biomarker | Canine TIMP-1 |
| Product Name | Anti-Canine TIMP-1 human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine TIMP-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine TIMP-1 antibodies in Canine TIMP-1 level test of animal Dog/Canine with coronary artery stenosis, coronary artery lesions. |
| Product description | Anti-Canine TIMP-1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a member of the TIMP family, which comprises four structurally related proteins that are known to regulate the activity of matrix metalloproteinases (MMPs). MMPs are zinc-dependent endopeptidases that are involved in the degradation of extracellular matrix (ECM) components, such as collagen, elastin, and proteoglycans. The balance between MMP activity and TIMPs is critical for ECM remodeling, tissue repair, and angiogenesis.
TIMP-1 is a secreted glycoprotein that is synthesized by various cells and tissues in animals, including canines/dogs. TIMP-1 has been shown to bind to the active site of MMPs, inhibiting their activity and preventing excessive ECM degradation. In addition to MMP inhibition, TIMP-1 has been shown to have MMP-independent functions, including promoting cell proliferation, differentiation, and apoptosis, as well as modulating immune responses, angiogenesis, and tissue repair processes.
TIMP-1 expression is regulated by various cellular processes, including growth factors, cytokines, and ECM components. Its expression has been detected in various cells and tissues in animals, including fibroblasts, endothelial cells, epithelial cells, and macrophages.
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