Canine neurogranin antibody and antigen (recombinant protein)

Diagnostic anti-Canine neurogranin antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-neurogranin-Ag01Canine neurogranin$3090.00
GMP-CAN-neurogranin-Ab01Anti-Canine neurogranin mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-neurogranin-Ab02Anti-Canine neurogranin mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-neurogranin-Ab03Anti-Canine neurogranin human monoclonal antibody (mAb)$3090.00
GMP-CAN-neurogranin-Ab04Anti-Canine neurogranin human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-neurogranin-Ag01
Product NameCanine neurogranin
Target/BiomarkerCanine neurogranin
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine neurogranin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in neurogranin level test of animal Dog/Canine with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsCanine neurogranin
Product descriptionRecombinant Canine neurogranin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-neurogranin-Ab01,GMP-CAN-neurogranin-Ab02
Target/BiomarkerCanine neurogranin
Product NameAnti-Canine neurogranin mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine neurogranin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine neurogranin antibodies in Canine neurogranin level test of animal Dog/Canine with Alzheimer Disease(AD).
Product descriptionAnti-Canine neurogranin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine neurogranin antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-neurogranin-Ab03,GMP-CAN-neurogranin-Ab04
Target/BiomarkerCanine neurogranin
Product NameAnti-Canine neurogranin human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine neurogranin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine neurogranin antibodies in Canine neurogranin level test of animal Dog/Canine with Alzheimer Disease(AD).
Product descriptionAnti-Canine neurogranin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine Neurogranin, a close homolog of its human counterpart, stands as an intriguing and neuron-centric biomarker within the neurobiology of dogs. This specialized protein assumes a central role in the canine brain, orchestrating the symphony of synaptic plasticity and memory formation. Its presence and functionality illuminate the neural pathways that underpin learning, memory, and cognition in our canine companions.

    Structurally, Canine Neurogranin boasts a unique configuration comprising IQ-like motifs, a characteristic feature that allows it to interact with calmodulin, a calcium-binding protein. This interaction serves as a molecular switch, modulating calcium signaling within neurons and fine-tuning synaptic strength. Such exquisite control over synaptic plasticity positions Neurogranin as a linchpin in the complex neural processes that facilitate memory consolidation and learning in dogs.

    Functionally, Canine Neurogranin is the conductor of the cognitive orchestra within a dog's brain. Its ability to enhance neurotransmission between neurons ensures that synaptic connections are optimized for information encoding and retention. This neural plasticity, orchestrated by Neurogranin, facilitates a dog's remarkable capacity to learn new commands, remember past experiences, and navigate their environment with agility.



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