Equine A1M antibody and antigen (recombinant protein)

Diagnostic anti-Equine A1M antibodies pairs and antigen for animal health (animal Equine/Horse Proteinuria, preeclampsia,) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-A1M-Ag01Equine A1M$3090.00
GMP-EQU-A1M-Ab01Anti-Equine A1M mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-A1M-Ab02Anti-Equine A1M mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-A1M-Ab03Anti-Equine A1M human monoclonal antibody (mAb)$3090.00
GMP-EQU-A1M-Ab04Anti-Equine A1M human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-A1M-Ag01
Product NameEquine A1M
Target/BiomarkerEquine A1M
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine A1M antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of animal Equine/Horse with Proteinuria, preeclampsia,.
TagHis
Reconized/Reactive SpecicsEquine A1M
Product descriptionRecombinant Equine A1M protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-A1M-Ab01,GMP-EQU-A1M-Ab02
Target/BiomarkerEquine A1M
Product NameAnti-Equine A1M mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine A1M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine A1M antibodies in Equine A1M level test of animal Equine/Horse with Proteinuria, preeclampsia,.
Product descriptionAnti-Equine A1M mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine A1M antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-A1M-Ab03,GMP-EQU-A1M-Ab04
Target/BiomarkerEquine A1M
Product NameAnti-Equine A1M human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine A1M antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine A1M antibodies in Equine A1M level test of animal Equine/Horse with Proteinuria, preeclampsia,.
Product descriptionAnti-Equine A1M mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine/Horse Alpha-1-Microglobulin (A1M) emerges as a versatile guardian of equine health, offering multifaceted protection against oxidative damage and tissue injury. Structurally, A1M is a glycoprotein characterized by its low molecular weight and intricate polypeptide chain, consisting of approximately 183 amino acids. Its primary site of synthesis is the liver, where it is meticulously crafted and subsequently released into the circulatory system, ready to execute its vital functions.

    At the core of A1M's significance lies its role as a stalwart defender against oxidative stress. This biomarker stands poised to intercept and neutralize free radicals, highly reactive molecules that, when left unchecked, can inflict extensive damage to cellular structures, including proteins, lipids, and DNA. By harnessing its antioxidant prowess, A1M shields equine cells from the ravages of oxidative stress, ensuring the preservation of cellular integrity.

    Beyond its antioxidant functions, A1M exhibits a remarkable capacity to counteract tissue injury. It achieves this by forming complexes with substances generated during tissue damage, thereby preventing their toxic effects. A1M's multifunctional nature extends to its ability to bind heme, a molecule released during the breakdown of hemoglobin. By sequestering heme, A1M curtails its potential for tissue harm, offering a crucial line of defense in situations like hemolysis or hemorrhage.



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