Equine GFAP antibody and antigen (recombinant protein)

Diagnostic anti-Equine GFAP antibodies pairs and antigen for animal health (animal Equine/Horse Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-GFAP-Ag01Equine GFAP$3090.00
GMP-EQU-GFAP-Ab01Anti-Equine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-GFAP-Ab02Anti-Equine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-GFAP-Ab03Anti-Equine GFAP human monoclonal antibody (mAb)$3090.00
GMP-EQU-GFAP-Ab04Anti-Equine GFAP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-GFAP-Ag01
Product NameEquine GFAP
Target/BiomarkerEquine GFAP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine GFAP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsEquine GFAP
Product descriptionRecombinant Equine GFAP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-GFAP-Ab01,GMP-EQU-GFAP-Ab02
Target/BiomarkerEquine GFAP
Product NameAnti-Equine GFAP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine GFAP antibodies in Equine GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine GFAP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine GFAP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-GFAP-Ab03,GMP-EQU-GFAP-Ab04
Target/BiomarkerEquine GFAP
Product NameAnti-Equine GFAP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine GFAP antibodies in Equine GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine GFAP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine GFAP, Glial Fibrillary Acidic Protein, serves as a guardian within the intricate tapestry of equine neurobiology. This protein, predominantly residing within the astrocytes of the central nervous system (CNS) of horses, plays multifaceted roles in maintaining the structural and functional integrity of the nervous system.

    Structurally, Equine GFAP is a member of the intermediate filament protein family, sharing genetic and functional homology with its counterparts in diverse species, including humans. Astrocytes, the primary reservoir of GFAP, rely on this protein for structural support and cytoskeletal resilience. Equine GFAP filaments form an elaborate network within astrocytes, contributing to their adaptability and their ability to respond to various challenges.

    Functionally, Equine GFAP plays a pivotal role in supporting neuronal health. Astrocytes, by nourishing neurons, regulating synaptic transmission, and modulating neurotransmitter levels, are integral to CNS function. Equine GFAP actively participates in these processes, ensuring the optimal functioning of the equine CNS.

    However, the significance of Equine GFAP extends beyond these foundational roles. In response to CNS injury, neuroinflammation, or neurodegenerative conditions, astrocytes undergo a transformative process known as astrogliosis. During astrogliosis, astrocytes become activated, leading to increased expression of GFAP. This upregulation serves as a protective and reparative response, as astrocytes encapsulate injured areas, isolate toxic substances, and support neuronal recovery.



    About GDU


    GDU

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