Equine H-FABP antibody and antigen (recombinant protein)

Diagnostic anti-Equine H-FABP antibodies pairs and antigen for animal health (animal Equine/Horse myocardial injury) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-H-FABP-Ag01Equine H-FABP$3090.00
GMP-EQU-H-FABP-Ab01Anti-Equine H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-H-FABP-Ab02Anti-Equine H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-H-FABP-Ab03Anti-Equine H-FABP human monoclonal antibody (mAb)$3090.00
GMP-EQU-H-FABP-Ab04Anti-Equine H-FABP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-H-FABP-Ag01
Product NameEquine H-FABP
Target/BiomarkerEquine H-FABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine H-FABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in H-FABP level test of animal Equine/Horse with myocardial injury.
TagHis
Reconized/Reactive SpecicsEquine H-FABP
Product descriptionRecombinant Equine H-FABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-H-FABP-Ab01,GMP-EQU-H-FABP-Ab02
Target/BiomarkerEquine H-FABP
Product NameAnti-Equine H-FABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine H-FABP antibodies in Equine H-FABP level test of animal Equine/Horse with myocardial injury.
Product descriptionAnti-Equine H-FABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine H-FABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-H-FABP-Ab03,GMP-EQU-H-FABP-Ab04
Target/BiomarkerEquine H-FABP
Product NameAnti-Equine H-FABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine H-FABP antibodies in Equine H-FABP level test of animal Equine/Horse with myocardial injury.
Product descriptionAnti-Equine H-FABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    H-FABP, or Heart-Fatty Acid Binding Protein, emerges as a pivotal biomarker in the intricate realm of equine (horse) physiology. This unassuming yet indispensable protein finds its primary expression within the heart muscle, or cardiomyocytes, where it orchestrates the regulation of fatty acid metabolism. Structurally, H-FABP is a cytoplasmic protein adorned with a distinct binding pocket that enables it to transport and facilitate the utilization of fatty acids—a fundamental energy source—within the equine cardiac muscle cells.

    The exclusive residence of H-FABP within the equine heart underscores its crucial role in assessing cardiac health. Under normal physiological circumstances, H-FABP levels in the bloodstream of horses remain relatively low. However, its concentration can surge significantly in response to cardiac stress or injury, rendering it a highly sensitive and specific diagnostic tool for veterinarians and a source of invaluable insights for equine enthusiasts.

    H-FABP's functional significance within the heart extends beyond its metabolic role. It is when the equine heart faces challenges that the true importance of H-FABP as a biomarker shines.

    In scenarios where cardiac ischemia or infarction occurs, such as a heart attack, a segment of the heart muscle becomes deprived of oxygen and nutrients due to a blocked artery. It is during this ischemic injury that H-FABP is released into the bloodstream. Consequently, elevated levels of H-FABP in a horse's blood can serve as an early indicator of myocardial damage, often preceding clinical symptoms. The rapid identification of such cardiac issues allows for prompt medical intervention, potentially limiting the extent of cardiac damage and enhancing the likelihood of a positive outcome.



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