Equine MPO antibody and antigen (recombinant protein)

Diagnostic anti-Equine MPO antibodies pairs and antigen for animal health (animal Equine/Horse vascular inflammation) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-MPO-Ag01Equine MPO$3090.00
GMP-EQU-MPO-Ab01Anti-Equine MPO mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-MPO-Ab02Anti-Equine MPO mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-MPO-Ab03Anti-Equine MPO human monoclonal antibody (mAb)$3090.00
GMP-EQU-MPO-Ab04Anti-Equine MPO human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-MPO-Ag01
Product NameEquine MPO
Target/BiomarkerEquine MPO
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine MPO antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MPO level test of animal Equine/Horse with vascular inflammation.
TagHis
Reconized/Reactive SpecicsEquine MPO
Product descriptionRecombinant Equine MPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-MPO-Ab01,GMP-EQU-MPO-Ab02
Target/BiomarkerEquine MPO
Product NameAnti-Equine MPO mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine MPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MPO antibodies in Equine MPO level test of animal Equine/Horse with vascular inflammation.
Product descriptionAnti-Equine MPO mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MPO antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-MPO-Ab03,GMP-EQU-MPO-Ab04
Target/BiomarkerEquine MPO
Product NameAnti-Equine MPO human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine MPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MPO antibodies in Equine MPO level test of animal Equine/Horse with vascular inflammation.
Product descriptionAnti-Equine MPO mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Myeloperoxidase (MPO) in horses, often referred to as an indispensable enzymatic component of the innate immune system, is primarily located within the neutrophils, a specialized subset of white blood cells. Neutrophils are the body's rapid response team against invading pathogens, and MPO plays an instrumental role in their antimicrobial arsenal.

    Structurally, MPO is a heme-containing enzyme, featuring iron atoms at its core. When neutrophils detect the presence of microbial threats, they deploy MPO into the surrounding environment as part of the immune defense. MPO's primary mission is to catalyze the conversion of hydrogen peroxide (H2O2) and chloride ions (Cl-) into hypochlorous acid (HOCl). HOCl is a highly potent and reactive antimicrobial agent, capable of rapidly neutralizing a diverse array of microorganisms, including bacteria, fungi, and viruses.

    MPO's antimicrobial prowess is multifaceted. It generates reactive oxygen species (ROS), such as superoxide radicals and hydrogen peroxide, which are toxic to pathogens. Additionally, it promotes the conversion of chloride ions into hypochlorous acid, further enhancing the neutrophils' ability to eliminate invaders.



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