Equine PA antibody and antigen (recombinant protein)

Diagnostic anti-Equine PA antibodies pairs and antigen for animal health (animal Equine/Horse liver disease, inflammation, or tissue death) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-PA-Ag01Equine PA$3090.00
GMP-EQU-PA-Ab01Anti-Equine PA mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PA-Ab02Anti-Equine PA mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PA-Ab03Anti-Equine PA human monoclonal antibody (mAb)$3090.00
GMP-EQU-PA-Ab04Anti-Equine PA human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-PA-Ag01
Product NameEquine PA
Target/BiomarkerEquine PA
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine PA antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PA level test of animal Equine/Horse with liver disease, inflammation, or tissue death.
TagHis
Reconized/Reactive SpecicsEquine PA
Product descriptionRecombinant Equine PA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PA-Ab01,GMP-EQU-PA-Ab02
Target/BiomarkerEquine PA
Product NameAnti-Equine PA mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PA antibodies in Equine PA level test of animal Equine/Horse with liver disease, inflammation, or tissue death.
Product descriptionAnti-Equine PA mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PA antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PA-Ab03,GMP-EQU-PA-Ab04
Target/BiomarkerEquine PA
Product NameAnti-Equine PA human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PA antibodies in Equine PA level test of animal Equine/Horse with liver disease, inflammation, or tissue death.
Product descriptionAnti-Equine PA mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Prothrombin Activation Fragment 1+2 (ePAF1+2) represents a crucial piece of the puzzle within the intricate world of equine hemostasis. Structurally, it arises as a fragment resulting from the activation of prothrombin (Factor II) into thrombin (Factor IIa), a process meticulously orchestrated by a cascade of coagulation factors and platelet interactions. This activation event is the cornerstone of blood clot formation, which is essential for maintaining hemostasis in horses.

    Prothrombin, an inactive precursor protein, circulates silently in the equine bloodstream until it encounters vascular injury. When such an injury occurs, a precisely choreographed sequence of enzymatic reactions is initiated, culminating in the cleavage of prothrombin into two fragments: thrombin and ePAF1+2. Thrombin, the multifunctional enzyme generated through this process, takes center stage in the creation of a stable blood clot. It catalyzes the conversion of soluble fibrinogen into insoluble fibrin strands, which provide the structural framework of a clot.

    ePAF1+2, while not directly involved in clot formation, plays a critical role as a marker of ongoing thrombin generation within the equine hemostatic system. Its presence in circulation reflects the dynamic equilibrium between prothrombin activation and thrombin regulation, offering insights into the coagulation status of horses.



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    GDU

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