Equine PTH antibody and antigen (recombinant protein)

Diagnostic anti-Equine PTH antibodies pairs and antigen for animal health (animal Equine/Horse Hyperparathyroidism) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-PTH-Ag01Equine PTH$3090.00
GMP-EQU-PTH-Ab01Anti-Equine PTH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PTH-Ab02Anti-Equine PTH mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PTH-Ab03Anti-Equine PTH human monoclonal antibody (mAb)$3090.00
GMP-EQU-PTH-Ab04Anti-Equine PTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-PTH-Ag01
Product NameEquine PTH
Target/BiomarkerEquine PTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine PTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Equine/Horse with Hyperparathyroidism.
TagHis
Reconized/Reactive SpecicsEquine PTH
Product descriptionRecombinant Equine PTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PTH-Ab01,GMP-EQU-PTH-Ab02
Target/BiomarkerEquine PTH
Product NameAnti-Equine PTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PTH antibodies in Equine PTH level test of animal Equine/Horse with Hyperparathyroidism.
Product descriptionAnti-Equine PTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PTH-Ab03,GMP-EQU-PTH-Ab04
Target/BiomarkerEquine PTH
Product NameAnti-Equine PTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PTH antibodies in Equine PTH level test of animal Equine/Horse with Hyperparathyroidism.
Product descriptionAnti-Equine PTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Within the intricate world of equine physiology, Equine Parathyroid Hormone (ePTH) stands as a sentinel, orchestrating the equilibrium of calcium and phosphate, fundamental to the well-being of horses. Structurally, it is a single-chain polypeptide hormone composed of 84 amino acids, primarily synthesized and secreted by the parathyroid glands, small structures nestled near the thyroid gland.

    The core function of ePTH lies in its responsiveness to deviations in ionized calcium levels within the equine bloodstream. When blood calcium levels dip below the optimal range, specialized calcium-sensing receptors within the parathyroid glands detect this perturbation and trigger the secretion of ePTH.

    ePTH, once released into circulation, embarks on a multi-faceted mission to restore calcium balance. Its primary target is the equine skeleton. Here, ePTH activates osteoclasts, specialized cells responsible for bone resorption. This process involves the breakdown of bone tissue, releasing stored calcium into the bloodstream. Simultaneously, ePTH enhances the reabsorption of calcium from urine in the kidneys, conserving this vital mineral.

    Furthermore, ePTH extends its influence to the gastrointestinal system by promoting the synthesis of calcitriol, the active form of vitamin D. Calcitriol, in turn, amplifies the absorption of dietary calcium in the equine intestines, completing the intricate loop of calcium regulation.



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    GDU

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