Equine Proinsulin antibody and antigen (recombinant protein)

Diagnostic anti-Equine Proinsulin antibodies pairs and antigen for animal health (animal Equine/Horse type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-Proinsulin-Ag01Equine Proinsulin$3090.00
GMP-EQU-Proinsulin-Ab01Anti-Equine Proinsulin mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Proinsulin-Ab02Anti-Equine Proinsulin mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Proinsulin-Ab03Anti-Equine Proinsulin human monoclonal antibody (mAb)$3090.00
GMP-EQU-Proinsulin-Ab04Anti-Equine Proinsulin human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-Proinsulin-Ag01
Product NameEquine Proinsulin
Target/BiomarkerEquine Proinsulin
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Proinsulin level test of animal Equine/Horse with type 2 diabetes.
TagHis
Reconized/Reactive SpecicsEquine Proinsulin
Product descriptionRecombinant Equine Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Proinsulin-Ab01,GMP-EQU-Proinsulin-Ab02
Target/BiomarkerEquine Proinsulin
Product NameAnti-Equine Proinsulin mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies in Equine Proinsulin level test of animal Equine/Horse with type 2 diabetes.
Product descriptionAnti-Equine Proinsulin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Proinsulin-Ab03,GMP-EQU-Proinsulin-Ab04
Target/BiomarkerEquine Proinsulin
Product NameAnti-Equine Proinsulin human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies in Equine Proinsulin level test of animal Equine/Horse with type 2 diabetes.
Product descriptionAnti-Equine Proinsulin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Proinsulin, an intricate 86-amino acid peptide hormone, holds a pivotal position in the intricate web of insulin biosynthesis within horses. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initial steps in insulin biosynthesis.

    The journey of Horse Proinsulin commences with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide is a distinguishing feature of proinsulin and plays a significant role in insulin biosynthesis.

    During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it regulates glucose metabolism by facilitating glucose uptake into cells.

    The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. Research suggests that the C-peptide may possess independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.



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