Equine S100-A9 antibody and antigen (recombinant protein)

Diagnostic anti-Equine S100-A9 antibodies pairs and antigen for animal health (animal Equine/Horse inflammatory bowel disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-S100-A9-Ag01Equine S100-A9$3090.00
GMP-EQU-S100-A9-Ab01Anti-Equine S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-S100-A9-Ab02Anti-Equine S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-S100-A9-Ab03Anti-Equine S100-A9 human monoclonal antibody (mAb)$3090.00
GMP-EQU-S100-A9-Ab04Anti-Equine S100-A9 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-S100-A9-Ag01
Product NameEquine S100-A9
Target/BiomarkerEquine S100-A9
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine S100-A9 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
TagHis
Reconized/Reactive SpecicsEquine S100-A9
Product descriptionRecombinant Equine S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-S100-A9-Ab01,GMP-EQU-S100-A9-Ab02
Target/BiomarkerEquine S100-A9
Product NameAnti-Equine S100-A9 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine S100-A9 antibodies in Equine S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
Product descriptionAnti-Equine S100-A9 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine S100-A9 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-S100-A9-Ab03,GMP-EQU-S100-A9-Ab04
Target/BiomarkerEquine S100-A9
Product NameAnti-Equine S100-A9 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine S100-A9 antibodies in Equine S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
Product descriptionAnti-Equine S100-A9 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    S100-A9 in horses (equines) emerges as a pivotal biomarker with multifaceted roles that transcend its status as a mere indicator. It plays a central role in equine health, inflammation, and immunity, with a diverse range of functions that underscore its significance in equine physiology.

    S100-A9, also known as calgranulin B, belongs to the S100 protein family, a group of calcium-binding proteins celebrated for their involvement in various cellular processes, particularly those related to inflammation and immune responses. In horses, S100-A9 takes center stage in the innate immune system, predominantly produced by neutrophils and monocytes.

    The hallmark of S100-A9's functionality lies in its ability to form a heterodimeric complex with S100-A8, collectively referred to as S100A8/A9 or calprotectin. This complex is released by activated neutrophils and monocytes in response to inflammatory cues, thus serving as a sentinel of the innate immune response. Upon release into the extracellular environment, S100A8/A9 exerts potent pro-inflammatory effects, orchestrating the recruitment of immune cells to sites of infection or injury.

    Beyond its role as an inflammatory mediator, S100-A9 is implicated in a multitude of cellular processes within the equine body. It contributes to cell adhesion, facilitating interactions between immune cells and the endothelium lining blood vessels. Moreover, it plays a role in cell differentiation and tissue repair, underscoring its multifunctional nature.

    Of significant note is S100-A9's function as a damage-associated molecular pattern (DAMP) molecule. It acts as a sentinel, alerting the immune system to tissue damage or infection, thus enabling a rapid immune response. This feature highlights its significance in equine physiology, where it serves as a versatile player in immune regulation and tissue homeostasis.



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    GDU

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