Equine TPO antibody and antigen (recombinant protein)
Diagnostic anti-Equine TPO antibodies pairs and antigen for animal health (animal Equine/Horse Hashimoto's disease or Graves' disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-EQU-TPO-Ag01 | Equine TPO | $3090.00 |
GMP-EQU-TPO-Ab01 | Anti-Equine TPO mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TPO-Ab02 | Anti-Equine TPO mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TPO-Ab03 | Anti-Equine TPO human monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TPO-Ab04 | Anti-Equine TPO human monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-EQU-TPO-Ag01 |
Product Name | Equine TPO |
Target/Biomarker | Equine TPO |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Equine TPO antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease. |
Tag | His | Reconized/Reactive Specics | Equine TPO |
Product description | Recombinant Equine TPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-TPO-Ab01,GMP-EQU-TPO-Ab02 |
Target/Biomarker | Equine TPO |
Product Name | Anti-Equine TPO mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Equine TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies in Equine TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease. |
Product description | Anti-Equine TPO mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-TPO-Ab03,GMP-EQU-TPO-Ab04 |
Target/Biomarker | Equine TPO |
Product Name | Anti-Equine TPO human monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Recombinant Equine TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies in Equine TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease. |
Product description | Anti-Equine TPO mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Thyroid Peroxidase (TPO) in horses (equines) stands as an unassuming yet pivotal biomarker, weaving the intricate tapestry of thyroid health, metabolic equilibrium, and overall vitality. Nestled predominantly within the thyroid gland, TPO conducts a symphony of enzymatic reactions critical to the synthesis of thyroid hormones.
The defining function of TPO revolves around its catalytic prowess, culminating in the iodination of tyrosine residues on thyroglobulin. Thyroglobulin, a substantial glycoprotein manufactured within thyroid follicular cells, serves as the raw material for thyroid hormone production. TPO's intervention initiates the formation of thyroxine (T4) and triiodothyronine (T3), two thyroid hormones that wield profound regulatory authority over metabolic pathways, energy utilization, thermoregulation, growth, and various physiological systems in horses.
TPO's catalytic mastery unfurls through a complex dance of iodination, wherein iodine atoms are judiciously incorporated onto specific tyrosine residues within thyroglobulin. This transformative process yields iodinated tyrosines, and subsequent coupling reactions between these iodinated tyrosines give rise to the biologically active thyroid hormones T4 and T3. These hormones represent the molecular maestros that govern the metabolic harmony of a horse's body.
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