Equine TPO antibody and antigen (recombinant protein)

Diagnostic anti-Equine TPO antibodies pairs and antigen for animal health (animal Equine/Horse Hashimoto's disease or Graves' disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-TPO-Ag01Equine TPO$3090.00
GMP-EQU-TPO-Ab01Anti-Equine TPO mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-TPO-Ab02Anti-Equine TPO mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-TPO-Ab03Anti-Equine TPO human monoclonal antibody (mAb)$3090.00
GMP-EQU-TPO-Ab04Anti-Equine TPO human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-TPO-Ag01
Product NameEquine TPO
Target/BiomarkerEquine TPO
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine TPO antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
TagHis
Reconized/Reactive SpecicsEquine TPO
Product descriptionRecombinant Equine TPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-TPO-Ab01,GMP-EQU-TPO-Ab02
Target/BiomarkerEquine TPO
Product NameAnti-Equine TPO mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies in Equine TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
Product descriptionAnti-Equine TPO mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-TPO-Ab03,GMP-EQU-TPO-Ab04
Target/BiomarkerEquine TPO
Product NameAnti-Equine TPO human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine TPO antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TPO antibodies in Equine TPO level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
Product descriptionAnti-Equine TPO mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Thyroid Peroxidase (TPO) in horses (equines) stands as an unassuming yet pivotal biomarker, weaving the intricate tapestry of thyroid health, metabolic equilibrium, and overall vitality. Nestled predominantly within the thyroid gland, TPO conducts a symphony of enzymatic reactions critical to the synthesis of thyroid hormones.

    The defining function of TPO revolves around its catalytic prowess, culminating in the iodination of tyrosine residues on thyroglobulin. Thyroglobulin, a substantial glycoprotein manufactured within thyroid follicular cells, serves as the raw material for thyroid hormone production. TPO's intervention initiates the formation of thyroxine (T4) and triiodothyronine (T3), two thyroid hormones that wield profound regulatory authority over metabolic pathways, energy utilization, thermoregulation, growth, and various physiological systems in horses.

    TPO's catalytic mastery unfurls through a complex dance of iodination, wherein iodine atoms are judiciously incorporated onto specific tyrosine residues within thyroglobulin. This transformative process yields iodinated tyrosines, and subsequent coupling reactions between these iodinated tyrosines give rise to the biologically active thyroid hormones T4 and T3. These hormones represent the molecular maestros that govern the metabolic harmony of a horse's body.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.