Equine TrxR antibody and antigen (recombinant protein)
Diagnostic anti-Equine TrxR antibodies pairs and antigen for animal health (animal Equine/Horse cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-EQU-TrxR-Ag01 | Equine TrxR | $3090.00 |
GMP-EQU-TrxR-Ab01 | Anti-Equine TrxR mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TrxR-Ab02 | Anti-Equine TrxR mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TrxR-Ab03 | Anti-Equine TrxR human monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-TrxR-Ab04 | Anti-Equine TrxR human monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-EQU-TrxR-Ag01 |
Product Name | Equine TrxR |
Target/Biomarker | Equine TrxR |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Equine TrxR antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TrxR level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth. |
Tag | His | Reconized/Reactive Specics | Equine TrxR |
Product description | Recombinant Equine TrxR protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-TrxR-Ab01,GMP-EQU-TrxR-Ab02 |
Target/Biomarker | Equine TrxR |
Product Name | Anti-Equine TrxR mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Equine TrxR antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TrxR antibodies in Equine TrxR level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth. |
Product description | Anti-Equine TrxR mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TrxR antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-TrxR-Ab03,GMP-EQU-TrxR-Ab04 |
Target/Biomarker | Equine TrxR |
Product Name | Anti-Equine TrxR human monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Recombinant Equine TrxR antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine TrxR antibodies in Equine TrxR level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth. |
Product description | Anti-Equine TrxR mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Equine Thioredoxin Reductase (TrxR) stands as a testament to the intricate biochemical machinery that safeguards the health of horses at the molecular level. This selenoprotein, distinguished by its dependence on the trace element selenium, plays a pivotal role within equine cells.
Structurally, Equine TrxR comprises a fascinating blend of amino acids and selenium, arranged meticulously to form an enzyme of paramount importance. Its active site, housing the selenium atom, acts as the catalytic center for the reduction of thioredoxin, a fundamental player in the cellular antioxidant defense system.
The primary function of Equine TrxR is to act as a vigilant guardian against the perils of oxidative stress. As horses go about their daily activities, their cells generate reactive oxygen species (ROS) as natural byproducts of metabolism. These ROS, if left unchecked, can wreak havoc within cells, causing damage to vital molecules such as proteins, lipids, and DNA. Equine TrxR steps in as the protector, diligently reducing the oxidized form of thioredoxin back to its active, reduced state. This restoration ensures that thioredoxin remains fully operational in its role of neutralizing ROS and maintaining the redox balance.
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