Feline ACTH antibody and antigen (recombinant protein)

Diagnostic anti-Feline ACTH antibodies pairs and antigen for animal health (animal Cat/Feline pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-ACTH-Ag01Feline ACTH$3090.00
GMP-FEL-ACTH-Ab01Anti-Feline ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ACTH-Ab02Anti-Feline ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ACTH-Ab03Anti-Feline ACTH human monoclonal antibody (mAb)$3090.00
GMP-FEL-ACTH-Ab04Anti-Feline ACTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-ACTH-Ag01
Product NameFeline ACTH
Target/BiomarkerFeline ACTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline ACTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACTH level test of animal Cat/Feline with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
TagHis
Reconized/Reactive SpecicsFeline ACTH
Product descriptionRecombinant Feline ACTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ACTH-Ab01,GMP-FEL-ACTH-Ab02
Target/BiomarkerFeline ACTH
Product NameAnti-Feline ACTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ACTH antibodies in Feline ACTH level test of animal Cat/Feline with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Feline ACTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ACTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ACTH-Ab03,GMP-FEL-ACTH-Ab04
Target/BiomarkerFeline ACTH
Product NameAnti-Feline ACTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ACTH antibodies in Feline ACTH level test of animal Cat/Feline with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Feline ACTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Adrenocorticotropic Hormone (ACTH) stands as a pivotal biomarker in the intricate web of feline endocrinology, orchestrating the cat's response to stressors and maintaining hormonal equilibrium. Structurally, ACTH is a 39-amino acid peptide hormone synthesized and secreted by the anterior pituitary gland. It belongs to the melanocortin family, a diverse group of hormones with multifaceted physiological roles.

    The primary mission of ACTH lies in its governance of the adrenal glands, specifically the adrenal cortex. When the feline body perceives stress or detects alterations in its internal milieu, the hypothalamus responds by releasing corticotropin-releasing hormone (CRH). CRH, in turn, kindles the anterior pituitary gland to unleash ACTH into the bloodstream.

    In its journey through circulation, ACTH reaches the adrenal cortex, where it binds to specific receptors adorning the surface of adrenal cells. This binding event ignites a cascade of intracellular processes culminating in the synthesis and release of cortisol, a corticosteroid hormone. Often referred to as the "stress hormone," cortisol exerts far-reaching effects on feline physiology.

    Cortisol wields the power to modulate metabolism, influence immune function, and dictate the feline response to stressors. It elevates blood glucose levels, tames immune responses, and orchestrates anti-inflammatory actions. Furthermore, cortisol influences protein and fat metabolism, maintains electrolyte balance, and bears influence on cardiovascular function.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.