Feline ANP antibody and antigen (recombinant protein)

Diagnostic anti-Feline ANP antibodies pairs and antigen for animal health (animal Cat/Feline hypertension, cardiac hypertrophy and heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-ANP-Ag01Feline ANP$3090.00
GMP-FEL-ANP-Ab01Anti-Feline ANP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ANP-Ab02Anti-Feline ANP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-ANP-Ab03Anti-Feline ANP human monoclonal antibody (mAb)$3090.00
GMP-FEL-ANP-Ab04Anti-Feline ANP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-ANP-Ag01
Product NameFeline ANP
Target/BiomarkerFeline ANP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline ANP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ANP level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
TagHis
Reconized/Reactive SpecicsFeline ANP
Product descriptionRecombinant Feline ANP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ANP-Ab01,GMP-FEL-ANP-Ab02
Target/BiomarkerFeline ANP
Product NameAnti-Feline ANP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline ANP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ANP antibodies in Feline ANP level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
Product descriptionAnti-Feline ANP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ANP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-ANP-Ab03,GMP-FEL-ANP-Ab04
Target/BiomarkerFeline ANP
Product NameAnti-Feline ANP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline ANP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline ANP antibodies in Feline ANP level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
Product descriptionAnti-Feline ANP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Atrial Natriuretic Peptide, or Feline ANP, stands as a remarkable component of the intricate cardiovascular system within domestic cats (Felis catus). Its origin lies in the atrial myocardium, specifically the atria, which are the heart's upper chambers responsible for receiving blood returning from the body and sending it to the ventricles for pumping into circulation.

    Structurally, Feline ANP is a peptide hormone composed of a chain of amino acids. Its synthesis and release are governed by the heart's sensitivity to changes in atrial pressure, primarily in response to the stretching of atrial walls. This mechanism comes into play during conditions that impose additional workload on the heart, such as increased blood volume or pressure within the atria.

    The role of Feline ANP within the feline body is truly remarkable. Its primary function is to maintain cardiovascular homeostasis by orchestrating a series of responses that help regulate blood pressure, fluid balance, and electrolyte levels. One of its most notable actions is the promotion of vasodilation, which leads to the relaxation of blood vessels. This process helps to alleviate the strain on the heart, reducing cardiac workload and ultimately contributing to enhanced cardiac function.

    Additionally, Feline ANP is a potent regulator of renal function. It enhances glomerular filtration rate (GFR) within the kidneys, which increases the rate at which blood is filtered to form urine. Moreover, Feline ANP inhibits sodium reabsorption in the renal tubules, facilitating increased sodium excretion in the urine. As sodium levels drop, water follows, aiding in the reduction of blood volume and blood pressure. These actions collectively contribute to the regulation of the body's fluid balance.



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