Feline Dig antibody and antigen (recombinant protein)

Diagnostic anti-Feline Dig antibodies pairs and antigen for animal health (animal Cat/Feline) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-Dig-Ag01Feline Dig$3090.00
GMP-FEL-Dig-Ab01Anti-Feline Dig mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Dig-Ab02Anti-Feline Dig mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Dig-Ab03Anti-Feline Dig human monoclonal antibody (mAb)$3090.00
GMP-FEL-Dig-Ab04Anti-Feline Dig human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-Dig-Ag01
Product NameFeline Dig
Target/BiomarkerFeline Dig
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline Dig antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Dig level test of animal Cat/Feline.
TagHis
Reconized/Reactive SpecicsFeline Dig
Product descriptionRecombinant Feline Dig protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Dig-Ab01,GMP-FEL-Dig-Ab02
Target/BiomarkerFeline Dig
Product NameAnti-Feline Dig mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline Dig antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Dig antibodies in Feline Dig level test of animal Cat/Feline.
Product descriptionAnti-Feline Dig mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Dig antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Dig-Ab03,GMP-FEL-Dig-Ab04
Target/BiomarkerFeline Dig
Product NameAnti-Feline Dig human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline Dig antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Dig antibodies in Feline Dig level test of animal Cat/Feline.
Product descriptionAnti-Feline Dig mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Dig, or digoxin in cats, is a biomarker of paramount importance in veterinary cardiology. It refers to the measurement of digoxin levels in the bloodstream of domestic cats (Felis catus). Digoxin is a cardiac glycoside medication that has been used for decades to treat a variety of heart conditions in both humans and feline patients.

    Digoxin exerts its therapeutic effects by inhibiting the sodium-potassium pump in cardiac muscle cells. This inhibition leads to an increase in intracellular calcium levels, which, in turn, enhances the force of cardiac muscle contraction while reducing heart rate. In cats with heart conditions such as congestive heart failure (CHF) and specific arrhythmias, digoxin is employed to improve cardiac function, alleviate symptoms, and extend life expectancy.

    The measurement of Feline Dig serves several crucial purposes. Firstly, it allows veterinarians to ascertain the concentration of digoxin in a cat's bloodstream, which is essential for maintaining the drug within the narrow therapeutic range. Cats, like humans, exhibit individual variability in drug metabolism and sensitivity, making precise dosing a challenge. Feline Dig monitoring ensures that the cat receives an appropriate dosage to achieve therapeutic effects without risking toxicity.

    Furthermore, Feline Dig measurement aids in assessing the cat's response to digoxin therapy over time. Cardiac conditions are dynamic, and the optimal dosage of digoxin may need adjustments as the cat's condition evolves. By regularly monitoring Feline Dig levels, veterinarians can tailor treatment plans to suit the individual needs of the patient, optimizing both efficacy and safety.



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