Feline HABP antibody and antigen (recombinant protein)

Diagnostic anti-Feline HABP antibodies pairs and antigen for animal health (animal Cat/Feline rheumatoid arthritis (RA) andosteoarthritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-HABP-Ag01Feline HABP$3090.00
GMP-FEL-HABP-Ab01Anti-Feline HABP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-HABP-Ab02Anti-Feline HABP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-HABP-Ab03Anti-Feline HABP human monoclonal antibody (mAb)$3090.00
GMP-FEL-HABP-Ab04Anti-Feline HABP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-HABP-Ag01
Product NameFeline HABP
Target/BiomarkerFeline HABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline HABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HABP level test of animal Cat/Feline with rheumatoid arthritis (RA) andosteoarthritis.
TagHis
Reconized/Reactive SpecicsFeline HABP
Product descriptionRecombinant Feline HABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-HABP-Ab01,GMP-FEL-HABP-Ab02
Target/BiomarkerFeline HABP
Product NameAnti-Feline HABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline HABP antibodies in Feline HABP level test of animal Cat/Feline with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Feline HABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline HABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-HABP-Ab03,GMP-FEL-HABP-Ab04
Target/BiomarkerFeline HABP
Product NameAnti-Feline HABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline HABP antibodies in Feline HABP level test of animal Cat/Feline with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Feline HABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline Hyaluronic Acid-Binding Protein (fHABP) emerges as a fundamental player in the intricate world of feline physiology. This glycoprotein, encoded by the fHABP gene, specializes in the orchestration of hyaluronic acid (HA), a prominent constituent of the extracellular matrix. HA's primary role is to maintain tissue hydration, lubrication, and resilience, and fHABP is its faithful guardian in the feline body.

    HA, a high molecular weight polysaccharide, resides in various tissues in cats, including connective tissues, skin, and synovial fluid. Its biophysical properties make it a vital component for proper joint function and overall tissue health. However, HA is prone to degradation and requires constant vigilance to maintain its integrity. This is where fHABP steps in. fHABP forms tight bonds with HA molecules, effectively shielding them from enzymatic degradation and environmental factors.

    The significance of fHABP becomes particularly evident in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating smooth articulation and reducing friction during movement. Without adequate HA levels and efficient HA-binding proteins like fHABP, joints may become susceptible to wear and tear, leading to conditions like osteoarthritis, a painful and debilitating ailment in cats.

    Moreover, fHABP's role extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. In doing so, it supports overall tissue integrity, wound healing, and the body's ability to withstand mechanical stress. Furthermore, fHABP interacts with other proteins and participates in various signaling pathways, influencing processes like tissue repair and inflammation.



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