Feline HER2 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-FEL-HER2-Ag01	Recombinant Feline HER2 protein	3090
GMP-FEL-HER2-Ab01	Anti-Feline HER2 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-HER2-Ab02	Anti-Feline HER2 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-HER2-Ab03	Anti-Feline HER2 human monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-HER2-Ab04	Anti-Feline HER2 human monoclonal antibody (mAb)	1953	20%	1562.4

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-HER2-Ag01
Product Name	Recombinant Feline HER2 protein
Target/Biomarker	Feline Epidermal Growth Factor Receptor 2 (HER2)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Epidermal Growth Factor Receptor 2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HER2 level test of animal Cat/Feline with breast cancer.
Tag	His
Products description	Recombinant Feline HER2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HER2-Ab01, GMP-FEL-HER2-Ab02
Product Name	Anti-Feline HER2 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Epidermal Growth Factor Receptor 2 (HER2)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Epidermal Growth Factor Receptor 2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HER2 antibodies in HER2 level test of animal Cat/Feline with breast cancer.
Tag	mFc
Products description	Anti-Feline HER2 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HER2 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HER2-Ab03, GMP-FEL-HER2-Ab04
Product Name	Anti-Feline HER2 human monoclonal antibody (mAb)
Target/Biomarker	Feline Epidermal Growth Factor Receptor 2 (HER2)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Epidermal Growth Factor Receptor 2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HER2 antibodies in HER2 level test of animal Cat/Feline with breast cancer.
Tag	hFc
Products description	Anti-Feline HER2 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HER2 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

The measurement of HER2 in cats has profound scientific and clinical significance. Firstly, it serves as a valuable diagnostic tool for identifying specific types of cancer, especially within the context of feline mammary gland tumors. HER2 overexpression is a common feature of some feline mammary tumors, and measuring HER2 levels can help veterinarians differentiate between tumor subtypes and assess tumor aggressiveness. This information is critical for developing treatment strategies tailored to the unique characteristics of each patient's cancer. Secondly, HER2-targeted therapies have emerged as a promising approach in the treatment of HER2-positive cancers in cats. These therapies aim to block the abnormal signaling of HER2, inhibiting uncontrolled cell growth. Accurate measurement of HER2 expression is essential for identifying cats that may benefit from these targeted treatments. Additionally, monitoring HER2 levels during treatment can provide insights into treatment response and guide adjustments to the therapeutic approach.

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