N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibody and antigen (recombinant protein)

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Diagnostic anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibodies pairs and antigen for animal health (animal Cat/Feline Heart failure, cardiac disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-NT-proBNP-Ag01	N-terminal prohormone of brain natriuretic peptide (NT-proBNP)	$3090.00
GMP-FEL-NT-proBNP-Ab01	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-NT-proBNP-Ab02	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-NT-proBNP-Ab03	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) human monoclonal antibody (mAb)	$3090.00
GMP-FEL-NT-proBNP-Ab04	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) human monoclonal antibody (mAb)	$3090.00

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Product Description

Cat No.	GMP-FEL-NT-proBNP-Ag01
Product Name	N-terminal prohormone of brain natriuretic peptide (NT-proBNP)
Target/Biomarker	not infectious
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level test of animal Cat/Feline with Heart failure, cardiac disease.
Tag	His
Reconized/Reactive Specics	N-terminal prohormone of brain natriuretic peptide (NT-proBNP)
Product description	Recombinant N-terminal prohormone of brain natriuretic peptide (NT-proBNP) protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-NT-proBNP-Ab01,GMP-FEL-NT-proBNP-Ab02
Target/Biomarker	not infectious
Product Name	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibodies in N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level test of animal Cat/Feline with Heart failure, cardiac disease.
Product description	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-NT-proBNP-Ab03,GMP-FEL-NT-proBNP-Ab04
Target/Biomarker	not infectious
Product Name	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibodies in N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level test of animal Cat/Feline with Heart failure, cardiac disease.
Product description	Anti-N-terminal prohormone of brain natriuretic peptide (NT-proBNP) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

N-terminal pro-B-type natriuretic peptide (NT-proBNP) in cats is a specialized and indispensable biomarker intricately linked to cardiac health. It is derived from the B-type natriuretic peptide (BNP) precursor molecule and plays a critical role in assessing feline cardiac health.

The synthesis and release of NT-proBNP in cats are intimately connected to cardiac function. Specifically, the ventricles of the heart, notably the left ventricle, are the primary source of NT-proBNP secretion. When these cardiac muscles experience stress, strain, or injury, such as in cases of hypertrophic cardiomyopathy (HCM), congestive heart failure (CHF), or other heart conditions, NT-proBNP is released into the bloodstream.

NT-proBNP serves as a highly sensitive and specific indicator of cardiac stress and dysfunction in cats. Its measurement allows veterinarians to evaluate the presence and severity of various cardiac diseases, facilitating early diagnosis and tailored treatment strategies.

The measurement of NT-proBNP levels in cats represents a groundbreaking development in the field of veterinary cardiology, offering profound insights into feline cardiac health. NT-proBNP is a highly specific and sensitive biomarker for cardiac issues, making it an indispensable diagnostic and prognostic tool for veterinarians.

One of the paramount applications of NT-proBNP measurement in cats is in the diagnosis and management of congestive heart failure (CHF). CHF can manifest as a consequence of diverse cardiac conditions, rendering its diagnosis and monitoring a complex challenge. Elevated NT-proBNP levels in cats not only confirm the presence of CHF but also provide valuable information about the severity of the condition.

Beyond CHF, NT-proBNP plays a pivotal role in diagnosing and monitoring other cardiac disorders commonly encountered in cats, such as hypertrophic cardiomyopathy (HCM). Early detection facilitated by NT-proBNP measurement empowers veterinarians to initiate timely interventions, tailor treatment plans to individual patient needs, and enhance the overall well-being and quality of life of feline patients.

In summary, N-terminal pro-B-type natriuretic peptide (NT-proBNP) in cats is a specialized and indispensable biomarker intricately linked to cardiac health. Its specific release from cardiac myocytes positions it as a highly sensitive and specific indicator of cardiac stress and dysfunction, particularly valuable in the early diagnosis and management of congestive heart failure and other feline cardiac conditions. By measuring NT-proBNP levels, veterinarians can provide advanced cardiac care, improve patient outcomes, and enhance the quality of life for cats with cardiac issues.

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