Feline TIMP-1 antibody and antigen (recombinant protein)

Diagnostic anti-Feline TIMP-1 antibodies pairs and antigen for animal health (animal Cat/Feline coronary artery stenosis, coronary artery lesions) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-TIMP-1-Ag01Feline TIMP-1$3090.00
GMP-FEL-TIMP-1-Ab01Anti-Feline TIMP-1 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TIMP-1-Ab02Anti-Feline TIMP-1 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-TIMP-1-Ab03Anti-Feline TIMP-1 human monoclonal antibody (mAb)$3090.00
GMP-FEL-TIMP-1-Ab04Anti-Feline TIMP-1 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-TIMP-1-Ag01
Product NameFeline TIMP-1
Target/BiomarkerFeline TIMP-1
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline TIMP-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TIMP-1 level test of animal Cat/Feline with coronary artery stenosis, coronary artery lesions.
TagHis
Reconized/Reactive SpecicsFeline TIMP-1
Product descriptionRecombinant Feline TIMP-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TIMP-1-Ab01,GMP-FEL-TIMP-1-Ab02
Target/BiomarkerFeline TIMP-1
Product NameAnti-Feline TIMP-1 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline TIMP-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TIMP-1 antibodies in Feline TIMP-1 level test of animal Cat/Feline with coronary artery stenosis, coronary artery lesions.
Product descriptionAnti-Feline TIMP-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TIMP-1 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-TIMP-1-Ab03,GMP-FEL-TIMP-1-Ab04
Target/BiomarkerFeline TIMP-1
Product NameAnti-Feline TIMP-1 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline TIMP-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline TIMP-1 antibodies in Feline TIMP-1 level test of animal Cat/Feline with coronary artery stenosis, coronary artery lesions.
Product descriptionAnti-Feline TIMP-1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    TIMP-1, also known as Tissue Inhibitor of Metalloproteinases-1, is a specific biomarker found in feline species. It belongs to the TIMP family, comprising TIMP-1, TIMP-2, TIMP-3, and TIMP-4. These biomarkers are endogenous inhibitors of matrix metalloproteinases (MMPs), enzymes responsible for the degradation of the extracellular matrix (ECM). Among the members of the TIMP family, TIMP-1 is extensively studied and characterized. It plays a crucial role in maintaining ECM homeostasis and regulating tissue remodeling processes in cats. TIMP-1 exerts its inhibitory effect on MMPs by forming complexes with them, preventing their enzymatic activity and subsequently controlling ECM turnover. The balance between MMPs and TIMPs is essential for normal physiological functions, such as wound healing, angiogenesis, and immune response modulation. Aberrant regulation of TIMP-1 expression has been implicated in various diseases, including cancer, fibrosis, cardiovascular disorders, and neurodegenerative conditions. In these pathological states, dysregulated TIMP-1 levels can disrupt the delicate ECM balance, leading to tissue damage, disease progression, and impaired healing processes. Therefore, quantifying TIMP-1 levels in feline models provides valuable insights into ECM dynamics, tissue remodeling, and associated diseases. Various techniques, such as ELISA, immunohistochemistry, or molecular analysis, can be employed to measure TIMP-1 concentrations in biological samples like serum, plasma, or tissues. Understanding the distinct properties and functions of TIMP-1 in cats contributes to improving diagnostic tools, therapeutic strategies, and overall feline health management.



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