Feline TIMP-1 antibody and antigen (recombinant protein)

Diagnostic anti-Feline TIMP-1 antibodies pairs and antigen for animal health (animal Cat/Feline coronary artery stenosis, coronary artery lesions) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to coronary artery stenosis, coronary artery lesions diagnostics products collection >>


Product information

Size: 1mg | 10mg | 100mg

Catalog No. Description US $ Price (per mg) First Order Discount First Order Discount Price
GMP-FEL-TIMP-1-Ag01 Recombinant Feline TIMP-1 protein 3090
GMP-FEL-TIMP-1-Ab01 Anti-Feline TIMP-1 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-FEL-TIMP-1-Ab02 Anti-Feline TIMP-1 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-FEL-TIMP-1-Ab03 Anti-Feline TIMP-1 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-FEL-TIMP-1-Ab04 Anti-Feline TIMP-1 mouse monoclonal antibody (mAb) 1953 20% 1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)



Product Description

Cat No. of Products GMP-FEL-TIMP-1-Ag01
Product Name Recombinant Feline TIMP-1 protein
Target/Biomarker Feline Matrix Metalloproteinase Inhibitor-1 (TIMP-1)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline Matrix Metalloproteinase Inhibitor-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TIMP-1 level test of animal Cat/Feline with coronary artery stenosis, coronary artery lesions.
Tag His
Products description Recombinant Feline TIMP-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-FEL-TIMP-1-Ab01, GMP-FEL-TIMP-1-Ab02, GMP-FEL-TIMP-1-Ab03, GMP-FEL-TIMP-1-Ab04
Product Name Anti-Feline TIMP-1 mouse monoclonal antibody (mAb)
Target/Biomarker Feline Matrix Metalloproteinase Inhibitor-1 (TIMP-1)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Anti-Feline Matrix Metalloproteinase Inhibitor-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TIMP-1 level test of animal Cat/Feline with coronary artery stenosis, coronary artery lesions.
Tag mFc
Products description Anti-Feline TIMP-1 mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    TIMP-1, also known as Tissue Inhibitor of Metalloproteinases-1, is a specific biomarker found in feline species. It belongs to the TIMP family, comprising TIMP-1, TIMP-2, TIMP-3, and TIMP-4. These biomarkers are endogenous inhibitors of matrix metalloproteinases (MMPs), enzymes responsible for the degradation of the extracellular matrix (ECM). Among the members of the TIMP family, TIMP-1 is extensively studied and characterized. It plays a crucial role in maintaining ECM homeostasis and regulating tissue remodeling processes in cats. TIMP-1 exerts its inhibitory effect on MMPs by forming complexes with them, preventing their enzymatic activity and subsequently controlling ECM turnover. The balance between MMPs and TIMPs is essential for normal physiological functions, such as wound healing, angiogenesis, and immune response modulation. Aberrant regulation of TIMP-1 expression has been implicated in various diseases, including cancer, fibrosis, cardiovascular disorders, and neurodegenerative conditions. In these pathological states, dysregulated TIMP-1 levels can disrupt the delicate ECM balance, leading to tissue damage, disease progression, and impaired healing processes. Therefore, quantifying TIMP-1 levels in feline models provides valuable insights into ECM dynamics, tissue remodeling, and associated diseases. Various techniques, such as ELISA, immunohistochemistry, or molecular analysis, can be employed to measure TIMP-1 concentrations in biological samples like serum, plasma, or tissues. Understanding the distinct properties and functions of TIMP-1 in cats contributes to improving diagnostic tools, therapeutic strategies, and overall feline health management.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

    Comments


    No comments yet.

    Leave a comment