Feline α-defensin 5 antibody and antigen (recombinant protein)

Diagnostic anti-Feline α-defensin 5 antibodies pairs and antigen for animal health (animal Cat/Feline Prosthetic joint infection (PJI)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-a-defensin-5-Ag01Feline α-defensin 5$3090.00
GMP-FEL-a-defensin-5-Ab01Anti-Feline α-defensin 5 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-a-defensin-5-Ab02Anti-Feline α-defensin 5 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-a-defensin-5-Ab03Anti-Feline α-defensin 5 human monoclonal antibody (mAb)$3090.00
GMP-FEL-a-defensin-5-Ab04Anti-Feline α-defensin 5 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-a-defensin-5-Ag01
Product NameFeline α-defensin 5
Target/BiomarkerFeline α-defensin 5
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline α-defensin 5 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of animal Cat/Feline with Prosthetic joint infection (PJI).
TagHis
Reconized/Reactive SpecicsFeline α-defensin 5
Product descriptionRecombinant Feline α-defensin 5 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-a-defensin-5-Ab01,GMP-FEL-a-defensin-5-Ab02
Target/BiomarkerFeline α-defensin 5
Product NameAnti-Feline α-defensin 5 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline α-defensin 5 antibodies in Feline α-defensin 5 level test of animal Cat/Feline with Prosthetic joint infection (PJI).
Product descriptionAnti-Feline α-defensin 5 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline α-defensin 5 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-a-defensin-5-Ab03,GMP-FEL-a-defensin-5-Ab04
Target/BiomarkerFeline α-defensin 5
Product NameAnti-Feline α-defensin 5 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline α-defensin 5 antibodies in Feline α-defensin 5 level test of animal Cat/Feline with Prosthetic joint infection (PJI).
Product descriptionAnti-Feline α-defensin 5 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    α-defensin 5, known as Def5 in scientific parlance, is a remarkable antimicrobial peptide found in the feline (cat) digestive system. It belongs to the α-defensin family, a group of small cationic peptides known for their potent antimicrobial properties. Within the feline physiology, α-defensin 5 assumes a pivotal role in the innate immune system, primarily within the small intestine.

    The production and secretion of α-defensin 5 primarily occur within specialized cells called Paneth cells. These cells are strategically located in the crypts of Lieberkühn, tiny invaginations within the intestinal mucosa. Paneth cells are responsible for maintaining the integrity of the intestinal epithelium and defending against potential microbial threats that may enter the digestive tract.

    Structurally, α-defensin 5 possesses a unique configuration of cysteine residues that form disulfide bonds. These bonds not only provide structural stability but also enhance its antimicrobial activity. The primary function of α-defensin 5 is to engage and neutralize a diverse array of pathogens, including bacteria, viruses, and fungi. By disrupting the integrity of microbial cell membranes, α-defensin 5 plays a vital role in the body's defense against invasive microorganisms.



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    GDU

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