Feline cIV antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-FEL-cIV-Ag01	Recombinant Feline cIV protein	3090
GMP-FEL-cIV-Ab01	Anti-Feline cIV mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-cIV-Ab02	Anti-Feline cIV mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-cIV-Ab03	Anti-Feline cIV mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-cIV-Ab04	Anti-Feline cIV mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-FEL-cIV-Ag01
Product Name	Recombinant Feline cIV protein
Target/Biomarker	Feline collagen type IV (cIV)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline collagen type IV antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of animal Cat/Feline with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag	His
Products description	Recombinant Feline cIV protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-cIV-Ab01, GMP-FEL-cIV-Ab02, GMP-FEL-cIV-Ab03, GMP-FEL-cIV-Ab04
Product Name	Anti-Feline cIV mouse monoclonal antibody (mAb)
Target/Biomarker	Feline collagen type IV (cIV)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Feline collagen type IV antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of animal Cat/Feline with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag	mFc
Products description	Anti-Feline cIV mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Feline Collagen Type IV (cIV) emerges as an unsung hero within the intricate realm of feline biology, quietly anchoring the structural integrity of the extracellular matrix. As a member of the collagen family, cIV boasts a triple helical structure comprising three distinct polypeptide chains, offering both resilience and flexibility—a true architectural masterpiece. Basement membranes, the domains where cIV reigns supreme, are far from passive spectators; they are dynamic command centers that orchestrate cellular interactions. These membranes provide critical support to epithelial and endothelial cell layers, all while mediating an intricate symphony of signaling processes. At the heart of this activity lies cIV, which not only forms the structural scaffold but also actively participates in molecular signaling events. Within basement membranes, cIV intertwines with other essential proteins and signaling molecules, generating a complex network of interactions. This network plays a pivotal role in regulating cellular behaviors, from adhesion to migration, and from growth to differentiation. In essence, cIV is the linchpin that keeps the basement membranes stable while orchestrating the nuanced dance of cellular communication.

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