Feline cTnI antibody and antigen (recombinant protein)

Diagnostic anti-Feline cTnI antibodies pairs and antigen for animal health (animal Cat/Feline Myocardial injury, heart disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-cTnI-Ag01Feline cTnI$3090.00
GMP-FEL-cTnI-Ab01Anti-Feline cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-cTnI-Ab02Anti-Feline cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-cTnI-Ab03Anti-Feline cTnI human monoclonal antibody (mAb)$3090.00
GMP-FEL-cTnI-Ab04Anti-Feline cTnI human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-cTnI-Ag01
Product NameFeline cTnI
Target/BiomarkerFeline cTnI
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline cTnI antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnI level test of animal Cat/Feline with Myocardial injury, heart disease.
TagHis
Reconized/Reactive SpecicsFeline cTnI
Product descriptionRecombinant Feline cTnI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-cTnI-Ab01,GMP-FEL-cTnI-Ab02
Target/BiomarkerFeline cTnI
Product NameAnti-Feline cTnI mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline cTnI antibodies in Feline cTnI level test of animal Cat/Feline with Myocardial injury, heart disease.
Product descriptionAnti-Feline cTnI mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline cTnI antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-cTnI-Ab03,GMP-FEL-cTnI-Ab04
Target/BiomarkerFeline cTnI
Product NameAnti-Feline cTnI human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline cTnI antibodies in Feline cTnI level test of animal Cat/Feline with Myocardial injury, heart disease.
Product descriptionAnti-Feline cTnI mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cardiac Troponin I (cTnI) is a protein of exceptional significance in the context of feline physiology. This cardiac-specific biomarker is predominantly found in the bloodstream of cats (felines) and serves as a crucial indicator of cardiac health. To truly appreciate the role of cTnI, it is essential to delve into its structural composition, functional significance, and its position within the realm of feline cardiology.

    Structurally, cTnI is one of the three subunits of the troponin complex, the other two being cardiac Troponin T (cTnT) and cardiac Troponin C (cTnC). The troponin complex resides within the sarcomeres of cardiac muscle fibers, where it meticulously regulates muscle contraction. This precision is vital for the rhythmic and efficient pumping of blood by the heart.

    What distinguishes cTnI is its exclusive cardiac specificity. While other troponin isoforms exist in skeletal muscle, cTnI is uniquely expressed in the heart. This specificity makes cTnI an exceptionally valuable biomarker for assessing cardiac muscle injury or damage. When cardiac cells are compromised due to factors such as Myocardial injury, heart disease, cardiac diseases, or cardiac trauma, cTnI is released into the bloodstream. Therefore, elevated levels of cTnI in a cat's blood can serve as a critical diagnostic indicator of cardiac health.

    Detecting cTnI levels in feline serum is typically achieved through immunoassays, such as enzyme-linked immunosorbent assays (ELISA). These assays provide a quantitative measure of cTnI concentration, enabling veterinarians to assess the extent of cardiac injury or disease. The sensitivity of these assays is such that even minor myocardial damage can lead to detectable elevations in cTnI levels, allowing for early diagnosis and intervention.



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