Feline sST2 antibody and antigen (recombinant protein)

Diagnostic anti-Feline sST2 antibodies pairs and antigen for animal health (animal Cat/Feline chronic and acute heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-sST2-Ag01Feline sST2$3090.00
GMP-FEL-sST2-Ab01Anti-Feline sST2 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-sST2-Ab02Anti-Feline sST2 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-sST2-Ab03Anti-Feline sST2 human monoclonal antibody (mAb)$3090.00
GMP-FEL-sST2-Ab04Anti-Feline sST2 human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-sST2-Ag01
Product NameFeline sST2
Target/BiomarkerFeline sST2
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline sST2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sST2 level test of animal Cat/Feline with chronic and acute heart failure.
TagHis
Reconized/Reactive SpecicsFeline sST2
Product descriptionRecombinant Feline sST2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-sST2-Ab01,GMP-FEL-sST2-Ab02
Target/BiomarkerFeline sST2
Product NameAnti-Feline sST2 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline sST2 antibodies in Feline sST2 level test of animal Cat/Feline with chronic and acute heart failure.
Product descriptionAnti-Feline sST2 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline sST2 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-sST2-Ab03,GMP-FEL-sST2-Ab04
Target/BiomarkerFeline sST2
Product NameAnti-Feline sST2 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline sST2 antibodies in Feline sST2 level test of animal Cat/Feline with chronic and acute heart failure.
Product descriptionAnti-Feline sST2 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Soluble ST2 (sST2) in cats is a soluble receptor intricately woven into feline cardiovascular health, playing a pivotal role in immune responses, inflammation regulation, and cardiac function. It represents a key component in the complex network of interactions that govern cardiac health and the body's response to cardiac stressors.

    In greater detail, sST2 is a product of the ST2 gene and exists in two primary forms: the membrane-bound ST2L and the soluble sST2. ST2L serves as a receptor for interleukin-33 (IL-33), an interleukin associated with anti-inflammatory and protective effects in the cardiovascular system. When IL-33 binds to membrane-bound ST2L, it contributes to cardiac protection and immune regulation.

    However, sST2, the soluble form of the ST2 receptor, acts as a decoy receptor, neutralizing the beneficial effects of IL-33. In cats, sST2 is predominantly secreted by cardiac cells, particularly cardiomyocytes, in response to various cardiac stressors, inflammation, or injury. Its presence in the bloodstream serves as a critical biomarker for assessing cardiac health and identifying cardiac pathologies.



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