tetrodotoxin(TTX) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-tetrodotoxin(TTX) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-tetrodotoxin(TTX)

OVA-tetrodotoxin(TTX)

Anti-tetrodotoxin(TTX) mouse monoclonal antibody

Anti-tetrodotoxin(TTX) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

1. Tetrodotoxin (TTX): Tetrodotoxin, commonly denoted as TTX, is a small yet potent molecule, primarily categorized as a neurotoxin rather than a mycotoxin. This classification places it within the broader realm of neurotoxins, specifically those found in marine organisms. TTX's significance is underscored by its profound impact on seafood safety and its complex scientific and regulatory dimensions.

1.1 Role in Marine Toxins:

Tetrodotoxin does not belong to the mycotoxin family; instead, it originates primarily from certain marine organisms, with pufferfish (genus Takifugu and others) being well-known TTX producers. However, TTX has also been identified in various other marine creatures, such as some species of blue-ringed octopuses and newts. TTX exerts its potent neurotoxic effects by interfering with normal nerve signal transmission. This disruption occurs through the blockade of sodium channels within cell membranes, leading to paralysis and, in severe cases, fatality. As a result, TTX holds a pivotal role in marine toxin research and the overarching concern of seafood safety.

2. Why Measure Tetrodotoxin (TTX)?

2.1 Ensuring Seafood Safety:

The meticulous measurement of Tetrodotoxin (TTX) is paramount to guarantee the safety of seafood products, particularly those derived from marine sources where TTX-producing organisms may be present. TTX is renowned as one of the most potent naturally occurring toxins, and its ingestion can result in severe health consequences, including paralysis and death. Therefore, precise TTX measurement is essential to identify and mitigate potential TTX contamination in seafood, ultimately safeguarding the well-being of consumers.

2.2 Regulatory Compliance:

Regulatory agencies worldwide have established stringent limits for TTX levels in seafood products to uphold public health and safety. Compliance with these established limits is a fundamental requirement for seafood producers and distributors. It ensures that their products adhere to safety standards and legal regulations. Failure to comply with these regulations can result in product recalls, market withdrawals, and legal repercussions for those responsible.

2.3 Preventing Poisoning Incidents:

TTX poisoning, often referred to as pufferfish poisoning or fugu poisoning, represents a grave health risk associated with the consumption of TTX-contaminated seafood. Accurate TTX measurement serves as a critical tool in preventing such poisoning incidents. By detecting contaminated seafood products and facilitating their swift removal from the market, TTX measurement plays a vital role in protecting consumers from harm and mitigating the associated health risks.

2.4 Supporting International Trade:

International trade in seafood products necessitates adherence to rigorous safety regulations and standards. The measurement of Tetrodotoxin (TTX) is vital to ensure that seafood exports meet the safety criteria specified by importing countries. By verifying TTX levels in seafood, exporters can demonstrate their commitment to delivering safe and compliant products, thus facilitating smooth and secure international trade.

2.5 Advancing Scientific Understanding:

Ongoing research and monitoring of TTX are essential components of the broader scientific effort to comprehensively understand its prevalence, sources, and potential mitigation strategies. This scientific inquiry contributes significantly to the development of effective monitoring techniques and the continuous improvement of safety measures within the seafood industry.

In conclusion, the meticulous measurement of Tetrodotoxin (TTX) is indispensable for the safety of seafood products, compliance with stringent regulatory guidelines, prevention of poisoning incidents, facilitation of international trade, and the advancement of scientific knowledge in the domain of marine toxins. Rigorous TTX quantification remains pivotal in protecting public health and ensuring the safety of seafood, particularly concerning the ever-present threat of TTX contamination in marine-derived products.

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