Cotinine (COT) antibody and antigen (hapten, BSA/OVA conjugated)

Diagnostic anti-Cotinine (COT) antibodies (anti-Cotinine, anti-COT) and diagnostic hapten-carrier conjugates BSA-Cotinine (COT), OVA-Cotinine (COT), KLH-Cotinine (COT) antigens for Inflammation/autoimmune/inflammatory disease COT detection in ELISA test, competitive ELISA, Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

Target products collectionGo to Inflammation/autoimmune/inflammatory disease diagnostics products collection>>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-228-Ag01BSA-Cotinine (COT)$756.00
GMP-SMT-228-Ag02OVA-Cotinine (COT)$756.00
GMP-SMT-228-Ab01Anti-human Cotinine (COT) mouse monoclonal antibody (mAb)$1953.00
GMP-SMT-228-Ab02Anti-human Cotinine (COT) human monoclonal antibody (mAb)$1953.00

Size: 1mg | 10mg | 100mg



Product Description

BSA-Cotinine (COT)

Cat No.GMP-SMT-228-Ag01
Product NameBSA-Cotinine (COT)
TargetCotinine (COT)
Expression platformSynthetic
Bioactivity validationCotinine (COT) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in COT level test of Inflammation/autoimmune/inflammatory disease and related syndrome evaluation
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Cotinine (COT) / OVA-Cotinine (COT) is Synthetic.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Cotinine (COT)

Cat No.GMP-SMT-228-Ag02
Product NameOVA-Cotinine (COT)
TargetCotinine (COT)
Expression platformSynthetic
Bioactivity validationCotinine (COT) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in COT level test of Inflammation/autoimmune/inflammatory disease and related syndrome evaluation
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Cotinine (COT) / OVA-Cotinine (COT) is Synthetic.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Cotinine (COT) mouse monoclonal antibody (mAb)

Cat No.GMP-SMT-228-Ab01
Product NameAnti-human Cotinine (COT) mouse monoclonal antibody (mAb)
TargetCotinine (COT)
Expression platformhybridoma
IsotypesMouse IgG
Bioactivity validationCotinine (COT) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Cotinine (COT) antibodies in COT level test of Inflammation/autoimmune/inflammatory disease and related syndrome evaluation.
TagmFc
Products descriptionAnti-human Cotinine (COT) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Cotinine (COT) human monoclonal antibody (mAb)

Cat No.GMP-SMT-228-Ab02
Product NameAnti-human Cotinine (COT) human monoclonal antibody (mAb)
TargetCotinine (COT)
Expression platformhybridoma
IsotypesHuman IgG1
Bioactivity validationCotinine (COT) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Cotinine (COT) antibodies in COT level test of Inflammation/autoimmune/inflammatory disease and related syndrome evaluation.
TaghFc
Products descriptionAnti-human Cotinine (COT) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Target/Biomarker information


    Cotinine and its Significance in In Vitro Diagnosis (IVD): Cotinine, a metabolite of nicotine found in tobacco products, holds significant importance in the realm of in vitro diagnosis (IVD). As a primary target molecule for diagnostic assays, our company specializes in providing anti-Cotinine antibodies and small molecule competitive antigens, including Carrier-coupled antigens, immunogens, hapten-carrier conjugates, Bovine Serum Albumin (BSA)-conjugated, and Ovalbumin (OVA)-conjugated forms. These meticulously engineered reagents are designed to facilitate the precise detection of Cotinine within various sample matrices.

    The Imperative of Cotinine Measurement:

    a. Tobacco and Nicotine Exposure Assessment: Cotinine serves as a reliable biomarker for evaluating tobacco and nicotine exposure. By quantifying Cotinine levels in bodily fluids like urine or blood, healthcare providers gain insights into an individual's exposure to tobacco smoke or nicotine-containing products. This assessment extends to both active and passive smoke exposure, making it invaluable in clinical and public health settings.

    b. Supporting Smoking Cessation Programs: Accurate Cotinine measurements are instrumental in smoking cessation programs. They allow individuals and healthcare professionals to monitor progress towards quitting smoking, tailor interventions, and provide targeted support. By tracking Cotinine levels over time, it becomes possible to gauge the effectiveness of smoking cessation strategies and adjust treatment plans accordingly.

    c. Maternal and Fetal Health: In the context of pregnancy, monitoring Cotinine levels is essential to protect maternal and fetal health. Elevated Cotinine levels in pregnant women may indicate active smoking, which can lead to adverse pregnancy outcomes such as preterm birth, low birth weight, and developmental issues. Cotinine testing during pregnancy is a preventive measure to identify and support pregnant individuals who smoke.

    d. Occupational and Insurance Screening: Cotinine testing is a common component of occupational health and insurance screening processes. It verifies an individual's tobacco use history, impacting insurance premiums and workplace policies. Employers may use Cotinine tests as part of workplace wellness programs to encourage smoking cessation and promote employee health.

    e. Research and Epidemiology: Cotinine assays play a pivotal role in epidemiological studies and research focused on understanding the health effects of tobacco and nicotine exposure. They provide valuable data for public health initiatives and policymaking. Researchers can use Cotinine measurements to explore the associations between smoking, nicotine exposure, and various health outcomes, including cardiovascular disease, respiratory conditions, and cancer.

    f. Environmental Exposure Assessment: Cotinine measurements are not limited to tobacco smoke exposure alone. They can also be applied to assess environmental exposure to nicotine and tobacco-related toxins. This is particularly relevant in settings where non-smokers may be exposed to secondhand smoke or other sources of environmental contamination.

    In summary, precise Cotinine measurement spans a spectrum of clinical, public health, and research applications. From assessing tobacco exposure and supporting smoking cessation efforts to safeguarding maternal and fetal well-being, informing public health policies, and exploring broader environmental exposures, our specialized anti-Cotinine antibodies and competitive antigens empower accurate Cotinine detection. This, in turn, contributes to enhanced healthcare outcomes, informed policy decisions, and the advancement of scientific knowledge in the field of tobacco and nicotine research.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.