Brucella abortus/Brucella melitensis BP26 antibody and antigen (recombinant protein)

Diagnostic anti-Brucella abortus/Brucella melitensis BP26 antibodies pairs and antigen for animal health (animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease Brucellosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P100-Tg003-Ag01 Recombinant Brucella abortus/Brucella melitensis BP26 protein $3090.00
GMP-VT-P100-Tg003-Ab01 Anti-Brucella abortus/Brucella melitensis BP26 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P100-Tg003-Ab02 Anti-Brucella abortus/Brucella melitensis BP26 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P100-Tg003-Ab03 Anti-Brucella abortus/Brucella melitensis BP26 human monoclonal antibody (mAb) $3090.00
GMP-VT-P100-Tg003-Ab04 Anti-Brucella abortus/Brucella melitensis BP26 human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P100-Tg003-Ag01
Product Name Recombinant Brucella abortus/Brucella melitensis BP26 protein
Pathogen Brucella abortus/Brucella melitensis
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Brucella abortus/Brucella melitensis BP26 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Brucellosis.
Tag His
Product description Recombinant Brucella abortus/Brucella melitensis BP26 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P100-Tg003-Ab01,GMP-VT-P100-Tg003-Ab02
Pathogen Brucella abortus/Brucella melitensis
Product Name Anti-Brucella abortus/Brucella melitensis BP26 mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Brucella abortus/Brucella melitensis BP26 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Brucella abortus/Brucella melitensis antibodies in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Brucellosis.
Product description Anti-Brucella abortus/Brucella melitensis BP26 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Brucella abortus/Brucella melitensis antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P100-Tg003-Ab03,GMP-VT-P100-Tg003-Ab04
Pathogen Brucella abortus/Brucella melitensis
Product Name Anti-Brucella abortus/Brucella melitensis BP26 human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Brucella abortus/Brucella melitensis BP26 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Brucella abortus/Brucella melitensis antibodies in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Brucellosis.
Product description Anti-Brucella abortus/Brucella melitensis BP26 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Pathogen Information


    Brucella abortus and Brucella melitensis are two closely related gram-negative bacteria that are responsible for causing an infectious disease called brucellosis. These bacteria belong to the Alphaproteobacteria group and are capable of surviving within host cells, making them particularly difficult to treat.

    The most common host for Brucella abortus is cattle, bison, and elk, while Brucella melitensis primarily infects sheep and goats. Both bacteria can also cause disease in humans, with Brucella melitensis being the more common cause of human infection. In humans, brucellosis usually manifests as flu-like symptoms, but if left untreated, it can progress to more serious complications such as arthritis and endocarditis.

    One of the key factors that contribute to the virulence of Brucella abortus and Brucella melitensis is their virB operon. This operon encodes a type IV secretion system that allows the bacteria to invade host cells and evade the immune system. The VirB protein complex is a critical component of this system, enabling Brucella to establish a chronic infection within its host.

    Diagnosis of brucellosis typically involves bacterial isolation via culture, serological tests such as the Rose Bengal test, and molecular methods utilizing PCR technology. Many diagnostic methods target specific genes such as the 16S rRNA gene, omp25, and omp31. Nucleic acid amplification tests (NAATs) have also been developed to detect the presence of Brucella DNA and RNA, often targeting the same genes as traditional PCR assays.

    Treatment of brucellosis can be challenging, as the bacteria are capable of surviving within host cells and are therefore less susceptible to antibiotics. Tetracyclines and rifampin are commonly used to treat brucellosis, but long-term treatment is often required to achieve a cure.

    Prevention of brucellosis in both animals and humans involves measures such as vaccination, proper hygiene, and testing and culling infected animals. Vaccination against Brucella abortus is available for use in cattle, while the vaccine for Brucella melitensis is primarily used in sheep and goats. In humans, prevention relies on avoiding consumption of raw or undercooked meat from infected animals and practicing good hygiene.

    In conclusion, Brucella abortus and Brucella melitensis are important pathogens that cause brucellosis in a variety of animal hosts and humans. Their ability to survive within host cells and evade the immune system makes them particularly challenging to diagnose and treat. Increased awareness, prevention, and early detection are critical for controlling the spread of this disease.



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