Diagnostic anti-Brucella abortus/Brucella melitensis Outer membrane protein 28（OMP28） antibodies pairs and antigen for animal health (animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease Brucellosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Genemedi produces core animal health diagnostic ingredients-validated anti-Brucella abortus/Brucella melitensis Outer membrane protein 28（OMP28） antibodies pairs and antigens for rapid test kit of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with Brucellosis to evaluate the  animal health of Multiple species (Ruminants, Swine/Porcine/Pig).

The paired antibodies are both monoclonal antibodies (mab).

All the antibodies and antigens of  animal disease test are suitable for in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT. The antibody can act as a capture antibody and detection antibody. Antigens are validated as positive control materials.

Brucella melitensis in the adult ewe is generally asymptomatic and self-limiting within about 3 months. However, because the organism may enter and cause necrosis of the chorionic villi and fetal organs, abortion or stillbirths may occur. Abortion usually occurs in the third trimester, after which the ewe will appear to recover. It has been reported that up to 20% of infected ewes may abort more than once. Rams will also be infected and may develop orchitis or pneumonia. The disease caused by B. ovis is manifested by clinical or subclinical infection of the epididymis, leading to epididymal enlargement and testicular atrophy. Brucella ovis causes decreased fertility. Brucella melitensis is the more common cause of brucellosis in goats. Brucella abortus has been shown to infect goats in natural and experimental infections, and B. ovis has also been shown to infect goats experimentally. Does infected with B. melitensis will also abort during the third trimester. Infections with B. abortus in cattle produce few clinical signs. There may be a brief septicemia during which organisms are phagocytosed by neutrophils and fixed macrophages in lymph nodes. In cows, the organism localizes in supramammary lymph nodes and udders and in the endometrium and placenta of pregnant cows. Infection may cause abortions after the fifth month, with resulting retained placentas. Permanent infection of the udder is common and results in shedding of organisms in milk. In bulls, the organism may cause unilateral orchitis and epidydimitis and involvement of the secondary sex organs. Organisms may be in the semen. In infected herds, lameness may also be a clinical sign.

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