Porcine reproductive and respiratory syndrome virus NP antibody and antigen (recombinant protein)

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Diagnostic anti-Porcine reproductive and respiratory syndrome virus NP antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease porcine reproductive and respiratory syndrome) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P111-Tg001-Ag01	Recombinant Porcine reproductive and respiratory syndrome virus NP protein	$3090.00
GMP-VT-P111-Tg001-Ab01	Anti-Porcine reproductive and respiratory syndrome virus NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P111-Tg001-Ab02	Anti-Porcine reproductive and respiratory syndrome virus NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P111-Tg001-Ab03	Anti-Porcine reproductive and respiratory syndrome virus NP human monoclonal antibody (mAb)	$3090.00
GMP-VT-P111-Tg001-Ab04	Anti-Porcine reproductive and respiratory syndrome virus NP human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P111-Tg001-Ag01
Product Name	Recombinant Porcine reproductive and respiratory syndrome virus NP protein
Pathogen	Porcine reproductive and respiratory syndrome virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Porcine reproductive and respiratory syndrome virus NP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Porcine reproductive and respiratory syndrome virus level test of animal Swine/Porcine/Pig infectious disease with porcine reproductive and respiratory syndrome.
Tag	His
Product description	Recombinant Porcine reproductive and respiratory syndrome virus NP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P111-Tg001-Ab01,GMP-VT-P111-Tg001-Ab02
Pathogen	Porcine reproductive and respiratory syndrome virus
Product Name	Anti-Porcine reproductive and respiratory syndrome virus NP mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Porcine reproductive and respiratory syndrome virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine reproductive and respiratory syndrome virus antibodies in Porcine reproductive and respiratory syndrome virus level test of animal Swine/Porcine/Pig infectious disease with porcine reproductive and respiratory syndrome.
Product description	Anti-Porcine reproductive and respiratory syndrome virus NP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine reproductive and respiratory syndrome virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P111-Tg001-Ab03,GMP-VT-P111-Tg001-Ab04
Pathogen	Porcine reproductive and respiratory syndrome virus
Product Name	Anti-Porcine reproductive and respiratory syndrome virus NP human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Porcine reproductive and respiratory syndrome virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Porcine reproductive and respiratory syndrome virus antibodies in Porcine reproductive and respiratory syndrome virus level test of animal Swine/Porcine/Pig infectious disease with porcine reproductive and respiratory syndrome.
Product description	Anti-Porcine reproductive and respiratory syndrome virus NP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Porcine reproductive and respiratory syndrome virus (PRRSV), also known as blue-ear pig disease virus or porcine arterivirus, is a member of the family Arteriviridae, genus Betaarterivirus. It infects domestic and wild pigs and is the causative agent for two types of diseases: reproductive failure in sows and respiratory disease in piglets and growing pigs.

PRRSV is an enveloped single-stranded positive-sense RNA virus with a non-segmented genome that comprises approximately 15 kilobases. The genome encodes at least 14 proteins, including structural proteins and non-structural proteins. The most significant protein is the viral envelope glycoprotein GP5, which binds to the receptor on host cells and mediates viral entry.

PRRSV infection in pigs primarily occurs via aerosol transmission and direct contact with infected animals, and the virus can persist for prolonged periods in pigs. The incubation period of PRRSV ranges from two to six days, and the duration of the disease can vary from acute to chronic.

Reproductive failure due to PRRSV can result in abortions, stillbirths, mummification of fetuses, and weak or malformed piglets. Sows infected with PRRSV have a higher risk of developing secondary bacterial infections such as postpartum dysgalactia syndrome, which leads to a reduction in milk production. In contrast, respiratory disease caused by PRRSV leads to fever, coughing, and difficulty breathing in affected animals. The severity of the respiratory disease can range from mild to severe, with morbidity rates reaching 100% and mortality rates ranging from 5% to 50%.

To detect PRRSV infection in pigs, several diagnostic methods are available. Serological tests, such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence assay (IFA), are commonly used to detect antibodies against PRRSV. These tests are useful for detecting past exposure to the virus but cannot detect acute infections.

Nucleic-acid based tests, including reverse transcription polymerase chain reaction (RT-PCR) and loop-mediated isothermal amplification (LAMP), can detect viral RNA in infected animals. RT-PCR is a highly sensitive and specific method that can detect low levels of viral RNA. The LAMP technique is rapid, sensitive, and does not require sophisticated equipment, making it ideal for field use.

Virus isolation is another method used to detect PRRSV infection. This method involves culturing the virus in cell culture systems, followed by identification and characterization of the virus using serological and molecular techniques.

In conclusion, PRRSV is a significant pathogen that causes significant economic losses to the swine industry worldwide. Effective control measures, including vaccination, biosecurity, and proper management practices, can help prevent the spread of PRRSV and minimize the impact of the disease on pig health.

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