Infectious Bronchitis Virus - Variant ItalyO2 S1 antibody and antigen (recombinant protein)

Diagnostic anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 antibodies pairs and antigen for animal health (animal Chicken infectious disease respiratory disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P150-Tg001-Ag01 Recombinant Infectious Bronchitis Virus - Variant ItalyO2 S1 protein $3090.00
GMP-VT-P150-Tg001-Ab01 Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P150-Tg001-Ab02 Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P150-Tg001-Ab03 Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 human monoclonal antibody (mAb) $3090.00
GMP-VT-P150-Tg001-Ab04 Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P150-Tg001-Ag01
Product Name Recombinant Infectious Bronchitis Virus - Variant ItalyO2 S1 protein
Pathogen Infectious Bronchitis Virus - Variant ItalyO2
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Infectious Bronchitis Virus - Variant ItalyO2 level test of animal Chicken infectious disease with respiratory disease.
Tag His
Product description Recombinant Infectious Bronchitis Virus - Variant ItalyO2 S1 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P150-Tg001-Ab01,GMP-VT-P150-Tg001-Ab02
Pathogen Infectious Bronchitis Virus - Variant ItalyO2
Product Name Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Infectious Bronchitis Virus - Variant ItalyO2 S1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant ItalyO2 antibodies in Infectious Bronchitis Virus - Variant ItalyO2 level test of animal Chicken infectious disease with respiratory disease.
Product description Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant ItalyO2 antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P150-Tg001-Ab03,GMP-VT-P150-Tg001-Ab04
Pathogen Infectious Bronchitis Virus - Variant ItalyO2
Product Name Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Infectious Bronchitis Virus - Variant ItalyO2 S1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant ItalyO2 antibodies in Infectious Bronchitis Virus - Variant ItalyO2 level test of animal Chicken infectious disease with respiratory disease.
Product description Anti-Infectious Bronchitis Virus - Variant ItalyO2 S1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen Information


    Infectious Bronchitis Virus - Variant ItalyO2: A Comprehensive Examination

    Infectious Bronchitis Virus - Variant ItalyO2 (IBV-ItalyO2) stands as a notable member of the Coronaviridae family, a group of viruses that has garnered widespread attention due to its implications for avian health, particularly in poultry, and its significant economic repercussions within the agricultural industry. This article delves into the intricate facets of IBV-ItalyO2, encompassing its nomenclature, classification, genetic composition, host specificity, associated diseases, and diagnostic methodologies.

    Nomenclature and Origin

    IBV-ItalyO2 is the product of rigorous virological investigation. Its name, like that of many viral variants, stems from its geographical origin, signifying the place of its discovery, Italy. This naming convention serves not only as an identifier but also as a critical reference point for researchers and epidemiologists tracking the spread and evolution of infectious bronchitis strains.

    Pathogen Classification

    IBV-ItalyO2 belongs to the realm of viruses, a diverse category of infectious agents. Specifically, it falls into the RNA virus category, which indicates that its genetic material is composed of ribonucleic acid (RNA), in contrast to the more common deoxyribonucleic acid (DNA) viruses. It is imperative to note that the RNA viruses exhibit a higher mutation rate, thus contributing to the dynamic nature of viral populations. Within the realm of RNA viruses, IBV-ItalyO2 finds its place within the Coronaviridae family. Furthermore, it is classified under the Gammacoronavirus genus, signifying its close relatives within this grouping. This positioning aids virologists in discerning key characteristics and behaviors of IBV-ItalyO2.

    Genetic Structure

    The genetic makeup of IBV-ItalyO2 is characterized by its primary gene of interest, the Spike (S) gene. This gene plays a pivotal role in the virus's structure and function. The S gene encodes the Spike protein, which has far-reaching implications for the pathogen's ability to infect host cells. The Spike protein's primary function is to bind to specific host cell receptors, initiating the process of viral entry. In essence, the S gene carries the genetic blueprint for this crucial protein, a critical determinant of the virus's infectivity.

    Host Specificity and Associated Diseases

    IBV-ItalyO2 has a pronounced affinity for avian hosts, with chickens being its primary target. Once this variant of the infectious bronchitis virus infects its host, it incites the pathogenesis of Infectious Bronchitis, a respiratory ailment known for its significant impact on poultry farming. The clinical manifestations of Infectious Bronchitis include coughing, sneezing, and nasal discharge, all of which contribute to a notable reduction in the overall well-being of the affected birds. Particularly concerning for poultry farmers is the reduction in egg production, a hallmark of this disease, especially in laying hens.

    Diagnostic Methodologies

    The accurate detection of IBV-ItalyO2 is fundamental for both the control of its spread and the mitigation of its impact on poultry populations. Diagnostic methods have evolved to encompass molecular techniques, prominently the Polymerase Chain Reaction (PCR). This sophisticated method targets specific genetic elements of the virus, allowing for the accurate identification of the pathogen. The primary genetic elements focused on in diagnostic tests are:

    Nucleocapsid (N) Gene: PCR assays designed for IBV-ItalyO2 detection target the N gene, a critical component of the viral genome.

    Spike (S) Protein: Some diagnostic methodologies emphasize the Spike protein as the target for antigen detection. This approach aids in the identification of the virus within infected hosts.

    Envelope (E) Protein: A subset of diagnostic assays may also incorporate the E protein, contributing to enhanced specificity in the identification process.



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