Proteus antibody and antigen (recombinant protein)

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Diagnostic anti-Proteus antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease urinary and septic infections) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P240-Tg001-Ag01	Recombinant Proteus protein	$3090.00
GMP-VT-P240-Tg001-Ab01	Anti-Proteus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P240-Tg001-Ab02	Anti-Proteus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P240-Tg001-Ab03	Anti-Proteus human monoclonal antibody (mAb)	$3090.00
GMP-VT-P240-Tg001-Ab04	Anti-Proteus human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P240-Tg001-Ag01
Product Name	Recombinant Proteus protein
Pathogen	Proteus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Proteus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Proteus level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary and septic infections.
Tag	His
Product description	Recombinant Proteus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P240-Tg001-Ab01,GMP-VT-P240-Tg001-Ab02
Pathogen	Proteus
Product Name	Anti-Proteus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Proteus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Proteus antibodies in Proteus level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary and septic infections.
Product description	Anti-Proteus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Proteus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P240-Tg001-Ab03,GMP-VT-P240-Tg001-Ab04
Pathogen	Proteus
Product Name	Anti-Proteus human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Proteus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Proteus antibodies in Proteus level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary and septic infections.
Product description	Anti-Proteus mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen Information

Proteus: Unveiling the Microbial Tapestry

At the heart of bacterial taxonomy lies the genus Proteus, a captivating realm within the family Enterobacteriaceae. This genus, encompassing various species such as Proteus mirabilis and Proteus vulgaris, stands as a testament to the microbial diversity inherent in the bacterial domain.

Classification and Structural Elegance:

Proteus, an exemplar of Gram-negative bacteria, adopts a prokaryotic form, distinguishing itself by the absence of a membrane-bound nucleus. The structural elegance of Proteus is manifested in its intricate cellular composition. A robust outer cell wall and inner cell membrane enshroud the bacterial cytoplasm, which harbors the genetic blueprint in the form of DNA.

Key to the adaptive prowess of Proteus are its structural appendages. Fimbriae, specifically the MR/P fimbriae in Proteus mirabilis, serve as molecular bridges facilitating adherence to host tissues. Complementary to this, flagella provide Proteus with motility, a critical attribute for bacterial survival and colonization.

The genomic landscape of Proteus unfolds with the prominence of virulence factors. Genes encoding hemolysin and urease capture the essence of its pathogenicity. Hemolysin, a cytolytic toxin, underscores the bacterium's capacity to disrupt host cells, while urease, a pivotal enzyme, exemplifies Proteus' adeptness at urea hydrolysis, a characteristic trait employed in clinical diagnostics.

Host-Pathogen Interplay:

Proteus, a versatile pathogen, traverses the interspecies divide, infecting not only humans but a spectrum of animal hosts. Within the human clinical landscape, Proteus mirabilis takes center stage in the context of urinary tract infections (UTIs). The ability of Proteus species to ascend the urinary tract and cause complicated UTIs adds a layer of complexity to its clinical manifestations.

Beyond UTIs, Proteus unveils its pathogenic potential in wound infections, where breaches in the skin's integrity provide an opportune niche for colonization. Furthermore, the bacterium occasionally asserts its presence in the realm of healthcare-associated infections, warranting vigilant surveillance and diagnostic acumen.

Diagnostic Odyssey:

The diagnostic odyssey of Proteus unfolds through an array of methodologies designed to unravel its microbial identity. Microbiological culture emerges as the foundational pillar, enabling the isolation of Proteus from diverse clinical specimens—urine, wound swabs, and blood, providing invaluable insights into the spectrum of infections it may incite.

Biochemical tests serve as discerning tools, demystifying Proteus from its bacterial counterparts. The indole test, citrate test, and urease test act as molecular detectives, unraveling the biochemical intricacies that characterize Proteus species.

In the era of molecular diagnostics, nucleic acid-based methods offer unprecedented precision. The 16S rRNA gene, a beacon of conservation in bacterial genomes, serves as a linchpin for broad-spectrum identification, encompassing Proteus within its purview. The ureC gene, a testament to Proteus' urease prowess, stands as a beacon for specific identification within the microbial tapestry.

Venturing further into the genomic realm, the scrutiny of virulence genes unravels Proteus' pathogenic signature. These genes, including those encoding hemolysin, provide molecular fingerprints, aiding in the discernment of distinct Proteus strains.

Conclusion:

In the microcosm of bacterial diversity, Proteus stands as a testament to adaptability and pathogenic ingenuity. From the elegant architecture of its cellular form to the complex interplay with diverse hosts, this genus reveals layers of scientific intrigue. Navigating the diagnostic landscape, from classical microbiology to cutting-edge molecular methodologies, unveils the multifaceted nature of Proteus, beckoning researchers and clinicians alike to delve deeper into its microbial tapestry.

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