Pseudomonas Elastase(lasB) antibody and antigen (recombinant protein)

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Diagnostic anti-Pseudomonas Elastase(lasB) antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P241-Tg001-Ag01	Recombinant Pseudomonas Elastase(lasB) protein	$3090.00
GMP-VT-P241-Tg001-Ab01	Anti-Pseudomonas Elastase(lasB) mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P241-Tg001-Ab02	Anti-Pseudomonas Elastase(lasB) mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P241-Tg001-Ab03	Anti-Pseudomonas Elastase(lasB) human monoclonal antibody (mAb)	$3090.00
GMP-VT-P241-Tg001-Ab04	Anti-Pseudomonas Elastase(lasB) human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P241-Tg001-Ag01
Product Name	Recombinant Pseudomonas Elastase(lasB) protein
Pathogen	Pseudomonas
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Pseudomonas Elastase(lasB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Pseudomonas level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections.
Tag	His
Product description	Recombinant Pseudomonas Elastase(lasB) proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P241-Tg001-Ab01,GMP-VT-P241-Tg001-Ab02
Pathogen	Pseudomonas
Product Name	Anti-Pseudomonas Elastase(lasB) mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Pseudomonas Elastase(lasB) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Pseudomonas antibodies in Pseudomonas level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections.
Product description	Anti-Pseudomonas Elastase(lasB) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Pseudomonas antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P241-Tg001-Ab03,GMP-VT-P241-Tg001-Ab04
Pathogen	Pseudomonas
Product Name	Anti-Pseudomonas Elastase(lasB) human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Pseudomonas Elastase(lasB) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Pseudomonas antibodies in Pseudomonas level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig infectious disease with urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections.
Product description	Anti-Pseudomonas Elastase(lasB) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Pseudomonas is a group of gram-negative bacteria that are widely distributed in the environment. These bacteria are well-known for their ability to adapt to various ecological niches due to their versatile metabolic processes and complex genome structures. The Pseudomonas genus includes more than 140 species, and some strains are known to cause infections in plants, animals, and humans.

Pseudomonas bacteria possess an intricate structure that helps them colonize different environments ranging from soil and water to plant and animal hosts. The bacterial cell wall has an outer membrane, and the peptidoglycan layer is composed of muramic acid and diaminopimelic acid. The outer membrane contains lipopolysaccharides, porins, phospholipids, and other membrane proteins involved in transport mechanisms.

One of the essential features of Pseudomonas bacteria is their genomic complexity, which allows them to adapt to diverse environments. The genome size of Pseudomonas varies from 4.1 to 7.2 megabases, depending on the species, and is divided into two chromosomes that encode for numerous proteins. Some of these proteins, such as flagellins, enable Pseudomonas bacteria to move in different environments, while others like siderophore synthesis proteins help with iron acquisition, a key nutrient for bacterial growth.

Pseudomonas bacteria are also known for their ability to produce a range of secondary metabolites, such as antibiotics, pigments, and biosurfactants. These compounds play different roles in the survival of Pseudomonas bacteria by facilitating nutrient acquisition, defense against predators, and communication among bacterial populations.

In terms of their host range, Pseudomonas bacteria can infect a broad range of hosts, including plants, animals, and humans. In plants, different species of Pseudomonas, such as Pseudomonas syringae, can cause diseases such as blight, leaf spot, and canker. Some Pseudomonas species form beneficial associations with plant roots, providing nutrients and protecting them from pathogenic microorganisms.

In animals and humans, Pseudomonas aeruginosa is one of the most significant clinical isolates of the genus. This bacterium is a leading cause of hospital-acquired infections, particularly in immunocompromised patients. Pseudomonas aeruginosa causes various infections, including urinary tract infections, pneumonia, sepsis, and skin infections. The bacteria can also infect the respiratory system of cystic fibrosis patients, leading to chronic lung infections.

The diagnosis of Pseudomonas infections involves both culture-based and molecular methods. Culture-based techniques can detect the presence of the bacterium in infected samples, such as blood, urine, sputum, or wound swabs. Selective media, such as cetrimide agar or MacConkey agar, are used for culturing Pseudomonas bacteria. Meanwhile, molecular methods like PCR and DNA sequencing can help identify specific genetic markers or virulence factors associated with Pseudomonas infections. Some of the commonly targeted genes and proteins for detection include the 16S rRNA gene, exotoxin A gene, lasB gene, and elastase gene.

In summary, Pseudomonas bacteria are highly adaptive microorganisms that can thrive in various environments, including soil, water, plants, animals, and humans. Their intricate genome structures and metabolic capabilities enable them to compete and survive in different ecological niches. While some strains have beneficial roles, others cause severe infections in plants, animals, and humans. Understanding the structure, function, and diversity of Pseudomonas bacteria is crucial in developing effective therapies and strategies for preventing and controlling Pseudomonas infections.

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