AD-associated neuaronal thread protein (AD7c-NTP) antibody and antigen (Recombinant protein)

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Diagnostic AD-associated neuaronal thread protein (AD7c-NTP) antibodies (anti-AD-associated neuaronal thread protein, anti-AD7c-NTP) and antigens (recombinant AD-associated neuaronal thread protein (AD7c-NTP) protein) for Neurodegenerative diseases AD7c-NTP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-AD7c-NTP-Ag01	Recombinant human AD7c-NTP Protein	$3090.00
GMP-h-AD7c-NTP-Ab01	Anti-human AD7c-NTP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-AD7c-NTP-Ab02	Anti-human AD7c-NTP mouse monoclonal antibody (mAb)	$1953.00
GMP-h-AD7c-NTP-Ab03	Anti-human AD7c-NTP human monoclonal antibody (mAb)	$1953.00
GMP-h-AD7c-NTP-Ab04	Anti-human AD7c-NTP human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Pruducts	GMP-h-AD7c-NTP-Ag01
Product Name	Recombinant human AD7c-NTP Protein
Target/Biomarker	AD-associated neuaronal thread protein (AD7c-NTP)
Alias of Target/Biomarker	#N/A
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	AD-associated neuaronal thread protein (AD7c-NTP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Products description	Recombinant Human protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-AD7c-NTP-Ab01,GMP-h-AD7c-NTP-Ab02
Product Name	Anti-human AD7c-NTP mouse monoclonal antibody (mAb)
Target/Biomarker	AD-associated neuaronal thread protein (AD7c-NTP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human AD-associated neuaronal thread protein (AD7c-NTP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other AD-associated neuaronal thread protein (AD7c-NTP) antibodies in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human AD7c-NTP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other AD-associated neuaronal thread protein (AD7c-NTP) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-AD7c-NTP-Ab03,GMP-h-AD7c-NTP-Ab04
Product Name	Anti-human AD7c-NTP human monoclonal antibody (mAb)
Target/Biomarker	AD-associated neuaronal thread protein (AD7c-NTP)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human AD-associated neuaronal thread protein (AD7c-NTP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other AD-associated neuaronal thread protein (AD7c-NTP) antibodies in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human AD7c-NTP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Dementia in Alzheimer's disease (AD) is ultimately due to cell loss. The AD-associated neuronal thread protein (AD7c-NTP) gene encodes a approximately 41 kD membrane-spanning phosphoprotein that causes apoptosis and neuritic sprouting in transfected neuronal cells. The AD7c-NTP gene is over-expressed in AD beginning early in the course of disease. In the brain, increased AD7c-NTP immunoreactivity is associated with phospho-tau-immunoreactive cytoskeletal lesions, but not with amyloid-beta accumulations. The levels of AD7c-NTP in postmortem brain tissue correlate with the levels measured in paired ventricular fluid samples, suggesting that the protein is secreted or released by dying cells into cerebrospinal fluid (CSF). In this regard, elevated levels of AD7c-NTP can be detected in both CSF and urine of patients with early or moderately severe AD, and the CSF and urinary levels of AD7c-NTP correlate with the severity of dementia. The newest configuration of the AD7c-NTP assay, termed "7c Gold", has greater than 90% aggregate results from a number of studies suggest that AD7c-NTP is an excellent biomarker that could be helpful in the routine clinical evaluation of elderly patients at risk for AD.

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