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AD-associated neuaronal thread protein (AD7c-NTP) antibody and antigen (Recombinant protein)
Diagnostic AD-associated neuaronal thread protein (AD7c-NTP) antibodies (anti-AD-associated neuaronal thread protein, anti-AD7c-NTP) and antigens (recombinant AD-associated neuaronal thread protein (AD7c-NTP) protein) for Neurodegenerative diseases AD7c-NTP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-h-AD7c-NTP-Ag01 | Recombinant human AD7c-NTP Protein | 3090 |
| GMP-h-AD7c-NTP-Ab01 | Anti-human AD7c-NTP mouse monoclonal antibody (mAb) | 1953 |
| GMP-h-AD7c-NTP-Ab02 | Anti-human AD7c-NTP mouse monoclonal antibody (mAb) | 1953 |
| GMP-h-AD7c-NTP-Ab03 | Anti-human AD7c-NTP human monoclonal antibody (mAb) | 1953 |
| GMP-h-AD7c-NTP-Ab04 | Anti-human AD7c-NTP human monoclonal antibody (mAb) | 1953 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. of Products | GMP-h-AD7c-NTP-Ag01 |
| Product Name | Recombinant human AD7c-NTP Protein |
| Target/Biomarker | AD-associated neuaronal thread protein(AD7c-NTP) |
| Expression platform | mammalian |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | AD-associated neuaronal thread protein (AD7c-NTP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation. |
| Products description | Recombinant human AD7c-NTP Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. of Products | GMP-h-AD7c-NTP-Ab01, GMP-h-AD7c-NTP-Ab02 |
| Product Name | Anti-human AD7c-NTP mouse monoclonal antibody (mAb) |
| Target/Biomarker | AD-associated neuaronal thread protein(AD7c-NTP) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Human AD-associated neuaronal thread protein (AD7c-NTP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other AD-associated neuaronal thread protein (AD7c-NTP) antibodies in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation. |
| Tag | mFc |
| Products description | Anti-human AD7c-NTP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. of Products | GMP-h-AD7c-NTP-Ab03, GMP-h-AD7c-NTP-Ab04 |
| Product Name | Anti-human AD7c-NTP human monoclonal antibody (mAb) |
| Target/Biomarker | AD-associated neuaronal thread protein(AD7c-NTP) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Human AD-associated neuaronal thread protein (AD7c-NTP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other AD-associated neuaronal thread protein (AD7c-NTP) antibodies in AD7c-NTP level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation. |
| Tag | hFc |
| Products description | Anti-human AD7c-NTP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
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Target/Biomarker information
Dementia in Alzheimer's disease (AD) is ultimately due to cell loss. The AD-associated neuronal thread protein (AD7c-NTP) gene encodes a approximately 41 kD membrane-spanning phosphoprotein that causes apoptosis and neuritic sprouting in transfected neuronal cells. The AD7c-NTP gene is over-expressed in AD beginning early in the course of disease. In the brain, increased AD7c-NTP immunoreactivity is associated with phospho-tau-immunoreactive cytoskeletal lesions, but not with amyloid-beta accumulations. The levels of AD7c-NTP in postmortem brain tissue correlate with the levels measured in paired ventricular fluid samples, suggesting that the protein is secreted or released by dying cells into cerebrospinal fluid (CSF). In this regard, elevated levels of AD7c-NTP can be detected in both CSF and urine of patients with early or moderately severe AD, and the CSF and urinary levels of AD7c-NTP correlate with the severity of dementia. The newest configuration of the AD7c-NTP assay, termed "7c Gold", has greater than 90% aggregate results from a number of studies suggest that AD7c-NTP is an excellent biomarker that could be helpful in the routine clinical evaluation of elderly patients at risk for AD.
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