pepsinogen I (PG I) antibody and antigen (Recombinant protein)

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Diagnostic pepsinogen I (PG I) antibodies (anti-pepsinogen I, anti-PG I) and antigens (recombinant pepsinogen I (PG I) protein) for Gastric disease PG I detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-PG-I-Ag01	Recombinant human PG I Protein	$3090.00
GMP-h-PG-I-Ab01	Anti-human PG I mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PG-I-Ab02	Anti-human PG I mouse monoclonal antibody (mAb)	$1953.00
GMP-h-PG-I-Ab03	Anti-human PG I human monoclonal antibody (mAb)	$1953.00
GMP-h-PG-I-Ab04	Anti-human PG I human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Pruducts	GMP-h-PG-I-Ag01
Product Name	Recombinant human PG I Protein
Target/Biomarker	pepsinogen I (PG I)
Alias of Target/Biomarker	#N/A
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	pepsinogen I (PG I) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of Gastric disease (atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) and related syndrome evaluation
Products description	Recombinant Human pepsinogen I (PG I) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PG-I-Ab01,GMP-h-PG-I-Ab02
Product Name	Anti-human PG I mouse monoclonal antibody (mAb)
Target/Biomarker	pepsinogen I (PG I)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human pepsinogen I (PG I) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other pepsinogen I (PG I) antibodies in PG I level test of Gastric disease (atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human PG I mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other pepsinogen I (PG I) antibodies.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts	GMP-h-PG-I-Ab03,GMP-h-PG-I-Ab04
Product Name	Anti-human PG I human monoclonal antibody (mAb)
Target/Biomarker	pepsinogen I (PG I)
Alias of Target/Biomarker	#N/A
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human pepsinogen I (PG I) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other pepsinogen I (PG I) antibodies in PG I level test of Gastric disease (atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human PG I mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species	Human
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

There are two main types of pepsinogen (PG), namely PG I (PG A) and PG II (PG C). Both of these types are produced in the essential cells in the stomach corpus and fundus and in mucous cervical cells. Unlike PG A, PG C is also produced in the Brunner glands in the proximal duodenum and in the pyloric glands in the antrum [8]. Serum pepsinogen levels reflect the morphological and functional status of the stomach mucosa, so they serve as markers of chronic atrophic gastritis [9]. Low levels of serum PG A and PG A / PG C are observed in patients with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer [8]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261308/

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