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AAV2 variant (Y444F) Rep-Cap plasmid (retina-validated serotype AAV-RC plasmid) | GeneMedi
AAV protocol Download AAV User Manual Download Capsid mutant - AAV serotype 2 variant (AAV2-(Y444F)) system - Introduction
GeneMedi's AAV2 variant (Y444F) Rep-Cap plasmid (retina-validated serotype AAV-RC plasmid), also named AAV2 variant(Y444F)-RC plasmid, is part of AAV2 variant(Y444F) packaging system. AAV2 variant(Y444F) Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV2 variant(Y444F) capsid protein.
You can produce AAV2 variant(Y444F) paticle in 293T cell line in high titer using GeneMedi's AAV2 variant (Y444F) Rep-Cap plasmid with GeneMedi's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
The tissue tropism of AAV2 variant (Y444F) vector has been validated in retina (retinal ganglion cells) by both intravitreal injection and sub-retinal injection., with potential applications in retina gene therapy.
| Product Name | Organization Type | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| AAV2 variant(Y444F) Rep-Cap plasmid Cat.No.:P-RC03 Serotype:AAV2 variant (Y444F) Size:5ug | Academic | 1719 | ||
| AAV2 variant(Y444F) Rep-Cap plasmid Cat.No.:P-RC03 Serotype:AAV2 variant (Y444F) Size:5ug | Industry R&D (excluding CRO&CDMO&CXO) | Inquiry | ||
| AAV2 variant(Y444F) Rep-Cap plasmid Cat.No.:P-RC03 Serotype:AAV2 variant (Y444F) Size:5ug | CRO&CDMO& CXO&CMC& Manufacturing company | Inquiry | ||
| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | ||||
| Shipping Cost: | 169.00 | |||
| Total: | ||||
AAV2 capsid variant (Y444F) tissue tropism and gene transduction (serotype-specific AAV infection)
The tissue tropism of AAV2 variant (Y444F) vector has been validated in retina (retinal ganglion cells) by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
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Virus and titer: AAV2 variant (Y444F) vector system, 1×1012 vg/ml Animal: mouse, C57, 2 months Infection site: retina Gene delivery method: subretinal cavity injection, 3μl Determine assay: 3 weeks post infection, wholemount, immunofluorescence microscopy
Other AAV Rep-Cap Plasmid
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